652 Proceedings of the Royal Society of Edinburgh. [Sess. 
Rate of Catalysis of Methyl Acetate by Anthranilic Nitrate. 
For comparison, a solution was catalysed at the same time by nitric 
acid of the same strength approximately as the nitrate solution. 
20 e.c. — Anthranilic Nitrate. 
8 
1 c.c. Methyl Acetate. 
5 c.c. ^ HNOo, 15 c.c. - KNOo. 
8 3 8 3 
1 c.c. Methyl Acetate. 
t. 
X. 
A- x. 
k. 
X. 
A — x. 
k 
16-3 
3-65 
19'45 
102-7 
3-68 
18-22 
(140-0) 
88-3 
14-0 
9-1 
104-9 
14-9 
8-0 
119-0 
144-0 
17-9 
5-2 
103-1 
18-8 
4-1 
119-3 
2100 
20-6 
2-5 
105-5 
20-8 
2-1 
113-6 
Mean 
104-0 
Mean 
. 117-3 
Hydrolysis at ~ x -25 = ” 2222 . 
8 1 1 ( *o 
It was thought possible that the apparently anomalous behaviour was 
not caused entirely by the amphoteric character of the base, but was due 
perhaps to the fact that in the example taken the hydrolysis was neither 
very great nor very small, and therefore more affected by errors in calcula- 
tion caused by flaws in the theory. It was therefore necessary to test a 
non-amphoteric base also, with about the same degree of hydrolysis. The 
most convenient one answering to this description was thiazole,* C 3 H 3 NS, 
and accordingly experiments were made on the rate of catalysis of methyl 
acetate and conductivity of thiazole hydrochloride. 
Conductivity . — In order to obtain a value for jul v — the molecular con- 
ductivity of the unhydrolysed salt — the conductivity was taken of a 
solution in which thiazole was molecular-normal, and hydrochloric acid 
sixteenth-normal. In this way the hydrolysis of the sixteenth-normal 
hydrochloride present was reduced very considerably. (This device f 
could not be adopted in the case of anthranilic hydrochloride on 
account of the very slight solubility of the base.) But Bredig’s plan is 
not applicable here in its simple form, because the hydrolysis is so great 
* Walker, Zeit. Physikal. Clhemt , vol. iv. p. 332. 
t Bredig, loc. cit ., p. 214. 
