A 
JOURNAL 
OF 
NATURAL PHILOSOPHY, CHEMISTRY, 
AND 
THE ARTS, 
OCTOBERy 1813. 
ARTICLE I. 
I Additional Observations on the Effects of Magnesia in prevent- 
ing an increased Formation of uric Acid ; with Remarks on 
the Influence of Acids upon the Composition of the Urine. 
William Thomas Brande, Esq. F. R. S. Prof Chem, 
R. I*. 
I N a paper which I had the honour of laying before this So- Beferen'-e to 
ciety, about three years ago, and which is published in the former paper. 
FPhilosophical Transactionsf, some cases are related, illustrating 
I the effects of magnesia in preventing an increased formation 
lOf uric acid, and some experiments are detailed, instituted with 
iZ view to discover its mode of action. 
Since that period, many opportunities have occurred, both to 
5Sir Everard Home and myself, of confirming its efficacy upon 
<a more extended scale, and of ascertaining the efficient treat- 
tmentof those cases in which magnesia is ineffectual, and in 
\which it has even been found to aggravate the complaint. 
To bring forward additional evidence in favour of the use of 
• From Phil. Trans. 1813. See Phil. Journal, XXVIII, 132. 
t For 1813, p. 106. 
VoL. XXXVI, — No. l66. G magnesia. 
