NOTES ON SPOEOZOA III. 
199 
Coccidiau (“Adelea” liartman ni)/ in wliicli the nuclear 
constitution and behaviour of the young schizont is very 
similar (cf. also below, Note IV, where the nucleus of Leu- 
cocytozoon is compared). 
To return now to the behaviour of the karyosome. The 
two subequal or unequal karyosomes result undoubtedly from 
the division of the original large, single karyosome, which 
takes place in a premitotic manner; for in a couple of 
instances I have found the centrodesmose still persisting (cf. 
fig. 42). There is no possible doubt about this division of 
the karyosome ; the process here appears to be just the same 
as in Karyoly'sus lacerta), and my having found it in both 
])arasites substantiates and corroborates Jollos’ account of this 
behaviour of the karyosome in the youug schizonts of this 
Coccidiau. While the early condition and behaviour of the 
karyosome during this period is thus completely paralleled by 
the above-described early phase of K. lacertae, the sub- 
sequent course of events differs slightly in the two parasites. 
In the Coccidiau, at a rather late stage, three or four karyo- 
sonies are present (fig. 43, also fig. 3, PI. 10), most of which 
are small and have obviously arisen by the further division of 
one or both of the two above-mentioned daughter-karyosonies 
(cf. also Jollos’ figure).^ That is to say, here the karyosome 
continues to be separate and distinct from the general nuclear 
substance (as is known from the ascertained further develop- 
ment), whereas in K. Iacerta3 the karyosomatic chromatin 
which is retained by the nucleus becomes distributed amongst 
the general chromatic substance and no longer distinguishable. 
It is necessary to emphasise this fact of the premitotic 
division of the karyosome because, in recent papers, Reichenow 
’ This parasite is regarded by Leger ( 16 ) as the type of a new genus, 
Chagasia. 
- It may lie recalled that Siedlecki himself, in his original description 
of this form, also states that tlie karyosome divides : thus, “ il [le 
karyosome] donne, par bourgeonnement, naissance a des karyosomes 
secondaires," and, again, “ surtout un karyosome, pairfois divise en deux 
ou trois fragments.” 
