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H. M. WOODCOCK. 
term, as a definite attribute of this body; tlins, Hartmann 
and Chagas (11) say: “Man kann daranfhin jetzt den 
Begriff des Karyosoms direkt von dem Vorhandensein eines 
Centrioles [Centrosoms] abhiingig machcn.” This notion 
lias been elaborated to sucli an extent that the whole karyo- 
some, that is to say, chromatin-nncleolns + centrosorne, has 
come to be regarded as a distinct entity, <a locomotor or 
kinetic centre; its chromatin is the “kinetic component,” 
while the surrounding chromatin, scattered through the 
nncleoplasm or nuclear sap, is the “generative component” 
(the second nuclear type of Hartmann and Chagas). 
Now, in my opinion, this idea of the karyosome is very 
forced, besides being really quite unsupported by any 
evidence. For one thing, I do not consider that the Avhole 
karyosome (i.e. chromatin-nucleolus + centrosome) can be 
regarded as representing a defiiiite unit or “ locomotor- 
centre ” ; it may happen, in fact, that the intrinsic division- 
centre is outside and distinct from the karyosome (as in 
Spongomonas, for example, figured by Hartmann and 
Chagas, and cf. also the “ nucleo-centrosome ” of Adelea 
zonula, according to Moroff (21). Again, the condition 
shown by the true Binucleata, the Trypanosomes and their 
a, Hies is quite against this interpretation. Here there are 
two separate nuclei — a locomotor nucleus (kinetonucleus) and 
a vegetative one (trophonucleus) ; to this, of course, Hartmann 
and Chagas assent, saying (loc. cit.) that “ zwei verschieden 
differenzierte Kerne in der Zelle vorhanden sind, einer 
[trophonucleus] vorwiegend mit der trophisch-generativen 
Komponente, der andere [kinetonucleus] vorwiegend mit der 
lokomotorischen Komponente.” But nothing is more certain 
than that the trophonucleus of a Trypanosome possesses a 
large, conspicuous karyosome, containing most of the 
chromatin of the nucleus, and also a distinct centrosome 
(centriole) ! If, therefore, the karyosome in this case is a 
trophic component (which is, indeed, the most reasonable 
view to take), whatever ground is there for supposing that, 
in the passive, intra-cellular Coccidian, the equally large and 
