218 
H. M. ^VO()DCOCK. 
Karyolysus, in a preceding note, is striking. This occur- 
rence is apparently infrequent,^ but the observation of it has 
considerably helped to influence me in my decision to relin- 
quish, as no longer tenable, the view I have formerly held 
respecting the origin and significajice of this much discussed 
element. Regarding this body (or bodies) in the light of the 
nuclear constitution existing in certain phases of “ Adelea,” 
and especially bearing in mind the fact that I have myself 
made knoivn above a similar karyosomatic condition in a 
blood-parasite, Karyolysus, the conclusion seems to be 
forced upon one that here also we have to do with a true 
karyosomatic element, and not, after all, with a body com- 
parable to the kinetonucleus of a binucleate Flagellate. 
In regard to the finer cytological points, the nucleus of 
these female gametocytes differs slightly from that of the 
early schizonts of “Adelea’^ and Karyolysus, as might 
indeed be expected when the different nature and subsequent 
development of the two types of indidual is borne in mind. 
In those cases where there are two unequal-sized karyo- 
somatic bodies (as I intend to designate these intensely 
staining elements in future), I cannot say whether they arise 
by the division of a single original one, in a primitotic 
manner, though I think this quite likely. I have not observed 
a spindle connecting them, but that may be because I have 
only found very few individuals in which there are two of 
these bodies. On the other hand, there is certainly a division- 
centre in connection with the central part of the nucleus, for 
not infrequently a distinct spindle (centrodesmose) is seen 
stretching between two granules, one of which stands out 
particularly from the more faintly stained chromatic material 
(figs. 1 1, 14). One of Berliner’s figures also show this centro- 
desmose. The two granules connected by this spindle appear 
to be situated at the peri])hery of the central mass, and one is 
usually larger and more prominent than the other. In one 
instance I have observed a spindle running frotn the larger 
‘ It is somewhat remarkable that, in Giemsa-stained smears, I have 
never noticed two of these structures associated with the nucleus. 
