CHANGES IN CHONDEJOSOMES. 
553 
Changes in Chondriosomes Occurring in Patho- 
logical Conditions. • 
By 
.1. O. Wakelin Barratt, 
From the Cancer Research Laljoratory, University of Liverpool. 
With 11 Text-figures. 
The structural characters of chondriosomes were first 
investigated in detail by Benda^ in a number of different 
cell types (renal cells, spermatids, marrow cells, leucocytes, 
striated muscle). 
Subsequently Meves,- by means of embryological observa- 
tions, studied the metamorphoses of chondriosomes® in rela- 
tion to differentiatiou of cell function, and showed that thereby 
different types of fibrils resulted, such as the cytoplasmic 
fibrils of epidermal cells, the fibrils of striped and unstriped 
muscle, neurofibrils, neuroglia fibres and connective-tissue 
fibres. 
Although the structural characters of chondriosomes have 
been studied iu detail, nevertheless the delimitation of mito- 
chondria is in some cases still uncertain, and the full signifi- 
cance of chondriosomes in respect of cell function has }mt to 
be determined. It has, however, been found possible in 
some cases, especially in respect of secreting cells, to form a 
* Benda, “ Weitere Mitteilungen fiber die Mitochondria,” ‘ Verh. d. 
Phys. Ges. zn Bej'lin,’ 1899. 
* Meves, “ Die Cliondriosoinen als Triiger erblicher Anlagen, Cyto- 
logische Studien am Hfilmerembryo,” ‘ Arch. f. Mikr. Anat.,’ 1908, B. 
72, S. . 
^ Mitochondria (/uVof , a thread ; x®v5po(,-, a grain) are granular ; chon- 
driokonts Ikovtoq, a pole) are rod-like. Chondriosome {aiofia, a body) is a 
general term applied to both varieties. Illustrations are given iu the 
figures. 
