566 
J. O. WAKELIN BAHRATT. 
S ummary. 
(1) The mitochondria of liepatic cells in pigmented de- 
generation of the liver assume a brownish-black colour and 
form the pigment-granules characteristic of this condition. 
(2) In severe liEemoglobinEemia the chondriosomes of the 
cells of the convoluted tubules are more readily demonstrable 
than in the normal condition, their staining capacity being 
increased. In this condition the mitochondrial elements 
reach an abnormally large size and are observed to take part 
in the elimination of hsemoglobin. 
(3) In pathological conditions in which rapid cell prolifera- 
tion is occurring, the chondriosomes of the prickle layer of 
the epidermis appear of large size and stain with unusual 
facility, details of their structure being readily observable. 
In this respect they contrast with normal epidermal chondrio- 
somes, which stain imperfectly. 
