125 
Training . Formal training programs in biological safety are being 
intensified. They are presented in geographical locations near centers 
of recombinant DNA research. The biohazard assessment information 
being developed under our intramural and extramural programs is 
rapidly incorporated into this training effort. 
( 
It has been recognized that research groups are likely to be more 
knowledgeable in the biology of the recombinant DNA system employed 
than in biohazard control measures. The NIH has undertaken a number 
of other initiatives since release of the Guidelines for developing courses 
in laboratory safety and training personnel in handling biohazards. For 
scientists who will become engaged in such research, the NIH has 
initiated a training course on basic principles of biohazard control. The 
purpose is to make researchers aware of the expertise that is required 
to control biohazards successfully and to provide guidance in gaining this 
expertise. The course involves both lectures and workshops. Orientation 
is toward physical containment methods appropriate for Pi, P2, and P3 
level biohazards. A comprehensive course manual providing an extensive 
reference of biohazard materials is given to each attendee. There is to 
be no provision for certifying proficiency. 
Other training initiatives are in progress. An instructors' manual 
is being prepared so that the basic biohazards course may be easily 
adopted and presented by institutions that may wish to establish formal 
training programs in biohazard control. The NIH is currently develop- 
ing training opportunities designed to prepare researchers to employ P4 
physical containment practices proficiently. Also, several NIH components 
continue to produce training aids, pamphlets, and materials on the broad 
subject area of biohazard control. These efforts will contribute to the 
training of scientists throughout the world in biohazard control techniques. 
The NIH will also conduct site inspections of all P4 facilities in 
which its grantees and contractors will engage in recombinant DNA 
research. This inspection program will examine the training provided 
both to the research staff and to personnel who are responsible for the 
operation of P4 facilities. 
VI. DESCRIPTION OF ALTERNATIVES 
A. No action. 
There were no specific comments directed to this suggested 
alternative. The text of the EIS, however, has been revised and 
updated. 
B. NIH Prohibition of Funding of All Experiments with 
Recombinant DNA 
Here too, the text has been revised to reflect current facts. 
