TABLE OF CONTENTS 
CALL TO ORDER 4 
PROPOSED AMENDMENT TO APPENDIX D OF THE NIH GUIDELINES 
REGARDING A HUMAN GENE TRANSFER PROTOCOL ENTITLED: THE 
TREATMENT OF PATIENTS WITH METASTATIC MELANOMA AND RENAL CELL 
CANCER USING IN VITRO EXPANDED AND GENETICALLY-ENGINEERED 
(NEOMYCIN PHOSPHOTRANSFERASE) BULK, CD8(+ ) AND/OR CD4(+ ) 
TUMOR INFILTRATING LYMPHOCYTES AND BULK, CD8(+ ) AND/OR CD4(+ ) 
PERIPHERAL BLOOD LEUKOCYTES IN COMBINATION WITH RECOMBINANT 
INTERLEUKIN-2 ALONE, OR WITH RECOMBINANT INTERLEUKIN-2 AND 
RECOMBINANT ALPHA INTERFERON /Dr. Economou 4 
PROPOSED AMENDMENT TO APPENDIX D OF THE NIH GUIDELINES 
REGARDING A HUMAN GENE THERAPY PROTOCOL ENTITLED: 
IMMUNOTHERAPY OF MALIGNANCY BY IN VIVO GENE TRANSFER 
INTO TUMORS /Dr. Nabel 16 
PROPOSED AMENDMENT TO APPENDIX D OF THE NIH GUIDELINES 
REGARDING HUMAN GENE TRANSFER PROTOCOL ENTITLED: 
RETROVIRAL-MEDIA TED GENE TRANSFER OF BONE MARROW CELLS 
DURING AUTOLOGOUS BONE MARROW TRANSPLANTATION FOR ACUTE 
LEUKEMIA /Dr. Cornetta 26 
REPORT FROM THE WORKING GROUP ON THE FUTURE ROLE OF THE 
RECOMBINANT DNA ADVISORY COMMITTEE/Drs. R. Murray, Childress, 
and B. Murray 37 
PROPOSED AMENDMENT TO APPENDIX D OF THE NIH GUIDELINES 
REGARDING A HUMAN GENE THERAPY PROTOCOL ENTITLED: A PHASE 
//// STUDY OF CELLULAR ADOPTIVE IMMUNOTHERAPY USING 
GENETICALLY MODIFIED CD8(+ ) HIV-SPECIFIC T CELLS FOR HIV- 
SEROPOSITIVE PATIENTS UNDERGOING ALLOGENEIC BONE MARROW 
TRANSPLANT/ Dr. Greenberg 41 
PROPOSED AMENDMENT TO APPENDIX D OF THE NIH GUIDELINES 
REGARDING A HUMAN GENE THERAPY PROTOCOL ENTITLED: 
LYMPHOKINE GENE THERAPY OF CANCER: PHASE I STUDY OF 
TUMOR IMMUNOTHERAPY WITH AUTOLOGOUS FIBROBLASTS GENETICALLY 
MODIFIED TO SECRETE INTERLEUKIN-2 /Dr. Sobol 50 
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Recombinant DNA Research, Volume 15 
