9 . 0 Study Parameters 
Parameters 
r~ 
Pre- Study 1 
Physical exam X 
History X 
Performance Status X 
Tumor Staging and/or 
Nodule Imaging X 
Chemistry Survey! X 
Vital Signs X 
Weight X 
CBC, Diff, Platelet X 
PT , PIT X 
EKG X 
CPK + isoenzymes X 
CXR X 
U/A and Culture X 
Hb s Ag, HIV X 
Brain CT or MRI X 
Assess for adverse X 
events status 
PCR on PBL and serum 
to detect HLA-B7 gene X 
Tumor biopsy X 
Assay for HLA-B7 
cytotoxic T cells X 
Assay for HLA-B7 
antibody X 
Pregnancy test 
(if relevant) X 
Anti-DNA antibodies X 
ds DNA 
ss DNA 
CT scan of brain 
(if relevant) X 
CT of chest & abdomen X 
Quantitate size of lesion X 
ANA, ESR , CH50, CRP X 
X 
X 
X 
X 
X 
X 
X 
X 
X 
3 
X 
X 
X 
X 
X 
X 
X 
During Treatment 
Day 
14 
X 
21 
1 r 
28 
X 
Week 
6 10 16 
X X 
1 
X X 
X 
X X 
X 
^-Routine laboratory tests include uric acid, calcium, phosphate, 
SGOT , SGPT , alkaline phosphatase, LDH, bilirubin, BUN, 
creatinine, total protein, glucose, amylase, lipase 
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