3.15) 
Patients must have an ECOG Performance 
Status of 2 or less. (See Table 1) 
3.16) 
Patients must have no evidence of active 
infection at the time of transplantation. 
3.17) 
Patients must be HIV 
nonreactive. 
3.18) 
Patients must have a pretransplant, 
multi-organ assessment: see Section 6.1. 
3.21 Criteria 
for Patient Ineliaibilitv 
3.21) 
Patients who have an estimated life 
expectancy of less than three months with 
bone marrow transplantation 
3.22) 
Patients who have an ECOG performance 
status greater than 2 (See Table 1) 
3.23) 
Patients who have angina and/or 
congestive heart failure requiring 
treatment, or who have had a myocardial 
infarction within the past year 
3.24) 
Patients who have a resting ejection 
fraction of less than 50% 
3.25) 
Patients who have severe renal disease as 
demonstrated by a serum creatinine 
greater than 2 . 0 mg/dL and/or a 
creatinine clearance less than 50 ml/min 
3.26) 
Patients who have any active soft tissue 
infection, sinus infection, dental 
infection, fungal infection or hepatitis 
including chronic active hepatitis; if 
the infection is successfully treated, 
the patient may be reconsidered for 
transplantation at a later date. 
3.27) 
Patients who have a positive HIV status 
3.28) 
Patients who have decreased pulmonary 
function due to any disorder as 
demonstrated by a diffusion capacity of 
less than 50% of predicted, a FEV! of 
less than 60% of predicted or a P02 of 
less than 80 mm Hg 
Recombinant DNA Research, Volume 15 
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