HUMAN GENE TRANSFER/THERAPY PROTOCOL 
9202-015 
Economou, James S. and Belldegrun, Arie, University of California at 
Los Angeles; The Treatment of Patients with Metastatic Melanoma and 
Renal Cell Cancer Using In Vitro Expanded and Genetically-Engineered 
(Neomycin Phosphotransferase) Bulk, CD8 (+) and/or CD4( + ) Tumor 
Infiltrating Lymphocytes and Bulk, CD8( + ) and/or CD4( + ) Peripheral 
Blood Leukocytes in Combination with Recombinant Interleukin-2 Alone, 
or with Recombinant Interleukin-2 and Recombinant Alpha Interferon. 
Date of RAC Approval: 2/11/92 
Date of NIH Approval: 4/17/92 
Recombinant DNA Research, Volume 15 
[511] 
