1 .0 CHECKLIST FOR PATIENT ELIGIBILITY AND NECESSARY INFORMATION 
NO YES 
Age less than 21 years at time of diagnosis 
Histologic proof of neuroblastoma 
Measurable evidence of disease 
Failure on conventional treatment 
Life expectancy of at least 8 weeks 
Performance status (ECOG) 0-2 
Recovered from toxic effects of prior chemotherapy 
ANC >500/mm 3 , Platelet count >50, 000/mm 3 (unless marrow replaced) 
Bilirubin <1.5 mg%, SGOT <,2x normal; prothrombin time normal; 
urinalysis normal 
Creatinine <1.5 mg% or creatinine clearance >80 mg/min/1.73 m 2 
Normal electrolytes, calcium, phosphorus, nutritional status 
To check eligibility or register patient call Dr. Furman at 531-2403 
or Dr. Brenner at 522-0410. 
Informed consent explained to and signed by patient/guardian 
Check table in Section 7.2 of this protocol to see necessary baseline 
and follow-up studies 
Exclusion Criteria 
Patients with: 
1. Rapidly progressive disease 
2. Active infection 
3. Need for concomitant drugs except analgesics 
4. Pregnancy or lactation 
5. Seropositive for HIV 
[746] 
Recombinant DNA Research, Volume 15 
