34. Handgretinger R, Bruehelt G, Kimming A, Dopier R, Niethammer D, Treuner J: In 
vitro induction of lymphokine-activated killer (LAK) activity in patients with 
neuroblastoma. Pediatr Hematol Oncol 6:307, 1989. 
35. Kim HS, Zhou M, Pais RC, Ingram N, Findley H, Ragab AH: Effect and kinetics of 
interleukin-2 (IL-2) in pediatric malignancies. Proc Annu Meet Am Assoc Cancer Res 
31:A1044, 1990 (abstr.). 
36. Reuland P, Klingebiel T, Dopfer R, Handgretinger R, Ehinger G, Feine U: 
Administration of interleukin 2 to a child with stage IV neuroblastoma after 
chemotherapy, therapy with (131)Iodo metaiodobenzyl-guanidine (mIBG), and bone 
marrow transplantation. Nuc Compact 20/4:138, 1989. 
37. Wexler C, Rosenberg SA et al. Unpublished. 
38. Fearon ER, Pardoll DM, Itaya T, Golumbek P, Levitsky HI, Simons JW, Karasuyama 
H, Vogelstein B, Frost P: Interleukin-2 production by tumor cells bypasses T helper 
function in the generation of an antitumor response. Cell 60:397, 1990. 
39. Blankenstein T, Qin ZH, Uberla K, Muller W, Rosen H, Volk HD, Diamantstein T: 
Tumor suppression after tumor cell-targeted tumor necrosis factor alpha gene transfer. 
J Exp Med 173:1047, 1991. 
40. Asher AL, Mule JJ, Kasid A, Restifo NP, Salo JC, Reichert CM, Jaffe G, Fendly B, 
Kriegler M, Rosenberg SA: Murine tumor cells transduced with the gene for tumor 
necrosis factor-alpha. Evidence for paracrine immune effects of tumor necrosis factor 
against tumors. J Immunol 146:3227, 1991. 
41. Russell SJ, Eccles SA, Flemming CL, Johnson CA, Collins MK: Decreased 
tumorigenicity of a transplantable rat sarcoma following transfer and expression of IL-2 
cDNA. Int J Cancer 47:244, 1991. 
42. Gansbacher B, Zier K, Daniels B, Cronin K, Bannerji R, Gilboa E: Interleukin 2 gene 
transfer into tumor cells abrogates tumorigenicity and induces protective immunity. J 
Exp Med 172:1217, 1990. 
43. Connor JP, Gansbacher B, Cronin K, heston W, Fair W, Gilboa E: A new approach 
to the immunotherapy of bladder cancer using IL-2 gene transfer into MBT-2 cells. 
Proc Annu Meet Am Assoc Cancer Res 32:A1475, 1991 (abstr.). 
44. Golumbek PT, Lazenby AJ, Levitsky HI, Jaffee LM, Karasuyama H, Baker M, Pardoll 
DM: Treatment of established renal cancer by tumor cells engineered to secrete 
interleukin-4. Science 254:713, 1991. 
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