It is not yet possible to say how helpful the vaccination treatments will be in 
shrinking kidney cancer, or what the optimal dose of altered tumor cells should be. 
This is a new technique that is currently being studied. The purpose of this study is 
to determine the safety of treatment with these altered renal cell carcinoma cells. 
SIDE EFFECTS 
In previous studies with x-rayed tumor cell vaccinations at Memorial Hospital, the 
side effects have been redness and swelling at the site of the injection. No one has 
had allergic reactions to the vaccines. 
The virus used to incorporate the blueprint for IL-2 is not able to grow on its own. 
In a recent study at the National Cancer Institute a similar virus has been used. 
Only a few patients received the virus, but so far there have been no serious side 
effects. There are no known additional risks to the normal cells in your body or to 
those people with whom you come into contact. However, this is a very new 
technique and serious side effects may yet be seen. There is a very remote 
possibility that the irradiated tumor cells used for the vaccination produce a virus 
not detected with our screening methods. Should a virus be produced there is the 
possibility that you may develop symptoms of a viral infection. Members of this 
virus family are known to cause lymphomas in rodents. Should you suffer a severe 
reaction to the vaccinations, treatment will be discontinued. 
You will be informed of the progress of the research study. During the time that 
you participate, you will be informed of any new findings which might affect your 
willingness to continue. 
If you are injured as a result of your participation in this research study, emergency 
care, hospitalization and outpatient care will be available to you by the Hospital and 
billed to you as part of your medical expenses. No money will be provided by 
Memorial Hospital or as compensation for a research-related injury. 
BENEFITS 
Although we do hope that this research study will be of benefit to you and others, 
there is not much experience in treating cancer patients with this technique and we 
do not know if this treatment will help you directly. 
FINANCIAL COST 
You are responsible for the costs of the physician visits, hospitalizations, and 
laboratory and diagnostic tests. There will be no charge for the growing of the 
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