* * * TABLE OF CONTENTS * * * 
I. Call to Order 6 
II. Minutes of March 1-2, 1993, Meeting 6 
III. Addition to Appendix D of the NIH Guidelines Regarding a Human Gene 
Therapy Protocol Entitled: Gene Therapy for the Treatment of Malignant Brain 
Tumors with In Vivo Tumor Transduction with the Herpes Simplex-Thymidine 
Kinase Gene/Ganciclovir System /Drs. Culver and Van Gilder 6 
IV. Addition to Appendix D of the NIH Guidelines Regarding a Human Gene 
Therapy Protocol Entitled: Phase I Study of Gene Therapy for Breast 
Cancer /Dr. Bank 14 
V. Addition to Appendix D of the NIH Guidelines Regarding a Human Gene 
Transfer Protocol Entitled: Administration of Neomycin Resistance Gene 
Marked EBV Specific Cytotoxic T Lymphocytes to Recipients of Mismatched- 
Related or Phenotypically Similar Unrelated Donor Marrow Grafts /Drs. Heslop, 
Brenner, Rooney 23 
VI. Addition to Appendix D of the NIH Guidelines Regarding a Human Gene 
Transfer Protocol Entitled: Assessment of the Efficacy of Purging by Using 
Gene-Marked Autologous Marrow Transplantation for Children with Acute 
Myelogenous Leukemia in First Complete Remission /Drs. Brenner, Krance, 
Heslop, Santana 26 
VII. Addition to Appendix D of the NIH Guidelines Regarding a Human Gene 
Therapy Protocol Entitled: A Phase I Trial of Human Gamma Interferon- 
Transduced Autologous Tumor Cells in Patients with Disseminated Malignant 
Melanoma /Dr. Seigler 29 
VIII. Addition to Appendix D of the NIH Guidelines Regarding a Human Gene 
Gene Therapy Protocol Entitled: Phase I Study of Non-Replicating Autologous 
Tumor Cell Injections Using Cells Prepared with or without Granulocyte- 
Macrophage Colony Stimulating Factor Gene Transduction in Patients with 
Metastatic Renal Cell Carcinoma /Dr. Simons 36 
IX. Addition to the Points to Consider of the NIH Guidelines Regarding 
Separation of the Gene Marking Informed Consent Document from the 
Therapeutic Informed Consent Documents/Dr. Post 42 
Recombinant DNA Research, Volume 17 
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