FF 
Principal Investigator/Program Director (Last, first, middle): 
HESLOP, Helen E. 
BIOGRAPHICAL SKETCH 
Give the following information for the key personnel and consultants and collaborators. Begin with the principal 
investigator/program director. Photocopy this page for each person. 
POSITION TITLE 
Assistant Member, Virology & Molecular Biology 
EDUCATION (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.) 
INSTITUTION AND LOCATION 
DEGREE 
YEAR 
CONFERRED 
FIELD OF STUDY 
University of East Anglia, England 
University of Cambridge, England 
B. Sc. 
Ph.D. 
1978 
1981 
Genetics 
Immunology 
RESEARCH AND PROFESSIONAL EXPERIENCE: Concluding with present position, list, in chronological order, previous employment, experience, and 
honors. Key personnel include the principal investigator and any other individuals who participate in the scientific development or execution of the project. 
Key personnel typically will include all individuals with doctoral or other professional degrees, but in some projects will include individuals at the masters or 
baccalaureate level provided they contribute in a substantive way to the scientific development or execution of the project. Include present membership on 
any Federal Government public advisory committee. List, in chronological order, the titles, all authors, and complete references to all publications during the 
past three years and to representative earlier publications pertinent to this application. DO NOT EXCEED TWO PAGES. 
Postdoctoral Fellow, (Department) University of Bristol, England 
Postdoctoral Fellow, Department of Cancer Studies, University of 
Birmingham, England 
Postdoctoral Fellow, Department of Epidemiology and Public Health, 
Yale University School of Medicine, New Haven, Connecticut 
Assistant Member, Ludwig Institute for Cancer Research, St. Mary's 
Hospital Medical School, London, England 
Abb let ant Member, Department of Virology and Molecular Biology, St. 
St. Jude Children's Research Hospital, Memphis, Tennessee ( 
PUBLICATIONS 
Rooney CM, Rickinson AB, Moss D J , Lenoir GM, Epstein MA. Paired Epstein-Barr virus- 1 
carrying lymphoma and lymphoblastoid cell lines from Burkitt's lymphoma patients: 
Comparative sensitivity to non-specific and to allospecific cytotoxic responses In vitro. 
Int J Cancer 34:339-348, 1984. 
€7 ' H 
Rooney CM, Rowe M, Wallace LE, Rickinson AB. Epstein-Barr virus positive Burkitt's 
lymphoma cells not recognized by virus-specific T-cell surveillance. Nature 317:629-631, 
1985. I 
1981-84 
1984- 85 
1985- 87 
1987-89 
1990 to 
Present 
NAME 
ROONEY, Cliona M. 
Rowe M, Rooney CM, Rickinson AB, Lenoir GM, Rupani H, Moss DJ, Stein H, Epstein MA. 
between endemic and sporadic forms of Epstein-Barr virus— positive Burkitt's . 
lymphoma. Int J Cancer 35:435-442, 1985. 
Rooney CM, Rowe M, Rickinson AB, Lenoir GM, Moss DM, Epstein MA. Endemic and sporadic J 
cases of Epstein-Barr virus positive Burkitt's lymphoma: Immunological characterization . 
of derived cell lines. Hamatol Bluttransfus 29:308-311, 1985. B 
_ ’ 
Rooney CM, Wimperis JZ, Brenner MK, Patterson J, Hoffbrand AV, Prentice HG. Natural j* 
killer cell activity following T-depleted allogenic bone marrow transplantation. Brit 
J Haematol 62:413-421, 1986. 
Rooney CM, Gregory CD, Rowe M, Finerty S, Edwards C, Rupani H, Rickinson AB. Endemic 
Burkitt s lymphoma: Phenotypic analysis of tumor biopsy cells and of the derived tumour 
cell lines. J Natl Cancer Inst 77:681-687, 1986. 
Rooney CM, Edwards CM, Lenoir GM, Rupani H, Rickinson AB. Differential activation of 
cytotoxic responses by Burkitt's lymphoma (BL) cell lines: Relationship to the BL 
Immunol 1 9 66. FF • 
Numbe(2«3«l =on secutively at the bottom throughout the application Do not use suffixeRftC917tEfllfl<int DNA RcSCBTCh, VolllIIlC 17 
