e. High index of suspicion is necessary for evaluation and treatment of 
interstitial pneumonitis in the post-BMT patient. Patients with low- 
grade fever and chronic cough should have prompt chest x-ray and 
pulmonary evaluation. FVC will be obtained two times a week for the 
first three weeks post-BMT and oximeter studies will be employed as 
necessary. 
f. To prevent activation of pneumocystis carinii (PCP) all patients will 
receive oral prophylaxis with trimethoprim (150 mg/m 2 /day) plus 
sulfamethoxazole (750 mg/m 2 /day) in two equally divided doses on 
Monday, Tuesday and Wednesday until day -1. Oral prophylaxis with 
trimethoprim/sulfamethoxazole will resume when the ANC >500/cu 
mm. 
13.0 EVALUATION DURING THERAPY 
13.1 Pre-Transplant 
1. History - complete history of previous antineoplastics, radiation 
therapy, infections, and transfusions 
2. Complete physical examination 
3. Laboratory screen 
a. CBC, differential, platelet estimate 
b. Electrolytes, BUN, creatinine, SGOT, SGPT, gamma GT, total 
bilirubin, total protein, albumin, alkaline phosphatase 
c. Urinalysis 
d. Chest x-ray 
e. Echocardiogram and EKG 
f. CPK isoenzymes, LDH 
g. Baseline pulmonary function tests (arterial blood gases if 
indicated) 
h. Coagulation screen 
Recombinant DNA Research, Volume 17 
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