CONTINUATION PAGE: STAY WITHIN MARGINS INDICATED 
Principal Investigator/Program Director (Last, first, middle): 
BRENNER, Malcolm K. 
Isfort RJ, Ihle N. Multiple hematopoietic growth factors signal through tyrosine r 
phosphorylation. Growth Factors 2:213-220, 1990. 
Morishita K, Parganas E, Parham DM, Matsugi T, Ihle JN. The Evi-1 zinc finger myeloid 
transforming gene is normall expressed in the kidney and in developing oocytes. Oncogene i4| 
5:1419-1423, 1990. 
Goldwasser E, Pech N, Ihle J. Interleukin 3 can compensate for the deficiency in 
erythroid burst-forming cells in anemic mice of genotype W/W w . Exp Hematol 18:936-939, 
1990. 
Ihle JN, Morishita K, Matsugi T, Bartholomew C. Insertional mutagenesis and 
transformation of hematopoietic stem cells. Prog Clin Biol Res 352:329-337, 1990. 
Bartholomew C, Ihle JN. Retroviral insertions 90 kb proximal to the Evi-1 myeloid 
transforming gene activate transcription from the normal promoter. 
11:1820-1828, 1991. 
Mol Cell Biol 
Stevens DA, Schreurs J, Ihle JN, May WS. Characterization of three related murine 
interleukin-3 surface receptor proteins. J Biol Chem 226 ( 7 ): 4151-4158, 1991. 
Yi T, Bolen JB, Ihle JN. Hematopoietic cells express two forms of lyn kinase differing 
by 21 amino acids in the amino terminus. Mol Cell Biol 11 ( 5 ): 2391-2398 , 1991. 
Wang WC, Crist WM, Ihle JN, Arnold BA, Keating JP. Granulocyte colony-stimulating factor 
corrects the neutropenia associated with glycogen storage disease type lb. 
5(4) :347-349, 1991. 
Leukemia 
Ihle JN. The Evi-1 zinc finger protein and transformation of hematopoietic progenitors. 
International Jounral Cell Cloning 9:1, 1991. 
Yi T, Cleveland JL, Ihle JN. Protein tyrosine phosphatase containing SH2 domains: 
characterization, preferential expression in hematopoietic cells, and localization to 
human chromosome 12;12-pl3. Mol Cell Biol 12:836-846, 1992. 
Mirua O, D 'Andrea A, Kabat D, Ihle JN. Induction of tyrosine phosphorylation by the 
erythropoietin receptor correlates with mitogenesis. Mol Cell Biol 11:4898-4902, 1991. 
Askew DA, Bartholomew C, Buchberg AM, Valentine MB, Jenkins NA, Copeland NG, Ihle JN. 
His-1 and His- 2: Identification and chromosomal mapping of two commonly rearranged sites 
of viral integration in a myeloid leukemia. Oncogene 6:2041-2047, 1991. 
Morishita K, Parganas E, Matsugi T, Ihle JN. Expression of the Evi-1 zinc finger gene 
in 32Dcl3 myeloid cells blocks granulocytic differentiation in response to G-CSF. Mol 
Cell Biol 12:183-189, 1991. 
Rill DR, Moen RC, Buschle M, Bartholomew C, Foreman NK, Mirro J Jr, Krance RA, Ihle JN, 
Brenner MK. An approach for the analysis of relapse and marrow reconstitution following 
autologous marrow transplantation using retrovirus mediated gene transfer. Blood 
79:2694-2700, 1992. 
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Rill DR, Buschle M, Foreman NK, Bartholomew C, Moen RC, Santana VM, Ihle JN, Brenner MK. 
Retrovirus mediated gene transfer as an approach to analyse neuroblastoma relapse after 
autologous bone marrow transfusion. Human Gene Therap 3:129-136, 1992. 
Furman WL, Lumm W, Arnold B, Pratt CB, Ihle JN. Recombinant human TNF-alpha stimulates 
the secretion of granulocytic colony-stimulating factor in vivo. Leukemia 6:319-322, 
1992. 
Morishita K, Parganas E, Willman CL, Whittaker MH, Drabkin H, Oval J, Taetle R, Ihle JN. 
Activation of Evi-1 gene expression in human acute myelogenous leukemias by 
rearrangements spanning 300-400 kb on chromosome 3q26. Proc Natl Acad Sci 89:3937-3941, 
DNA Research, Volume 17 
J. 
