PRINCIPAL INVESTIGATOFVPROGRAM DIRECTOR: 
Jonathan W. Simons 
»- ■ '* f * 
BIOGRAPHICAL SKETCH 
Give the following Information for the key personnel and consultants listed on page 2. Begin with the Principal 
Investigator/Program Director. Photocopy this page tor each person. 
NAME 
Jonathan W, 
Simons, M.D. 
MmfiMrofessor of 
Oncology and Urology 
BIRTHDATE (Mo., Day, Yr.) 
11/18/58 
EDUCATION (Begin with baccalaureate or other initial professional education, such as 
nursing, and include postdoctoral training.) 
INSTITUTION AND LOCATION 
DEGREE 
YEAR 
CONFERRED 
FIELD OF STUDY 
Princeton University, Princeton, NJ 
The Johns Hopkins University 
School of Medicine, Baltimore, MD 
A. B . 
M.D. 
1980 
1985 
Biochemistry 
Medicine 
RESEARCH AND PROFESSIONAL EXPERIENCE: Concluding with present position, list, in chronological order, previous employment, experience 
and honors. Include present membership on any Federal Government public advisory committee. List, in chronological order, the titles and com 
plete references to all publications during the past three years and to representative earlier publications pertinent to this application. DO NOT 
EXCEED TWO PAGES. 
1985- 86 
1986- 88 
1988- 90 
1989- 90 
1990- 91 
1991- 
1991- 
1992 
Intern, Internal Medicine, Massachusetts General Hospital, Harvard Medical 
School, Boston, Massachusetts 
Junior and Senior Resident, Internal Medicine, Massachusetts General 
Hospital, Harvard Medical School, Boston, Massachusetts 
Clinical Fellow, The Oncology Center, The Johns Hopkins University 
School of Medicine, Baltimore, Maryland 
Postdoctoral Fellow, The Oncology Center, The Johns Hopkins School of 
Medicine, Laboratory of Molecular Genetics, Baltimore, Maryland 
Assistant in Oncology, The Johns Hopkins University School of Medicine, 
Baltimore, Maryland 
Active, Full-Time Staff in Oncology, The Johns Hopkins Hospital 
Instructor In Oncology, The Johns Hopkins University School of Medicine, 
Baltimore, Maryland 
Assistant Professor in Oncology and Urology, The Johns Hopkins University 
School of Medicine, Baltimore, Maryland 
Honors 
1980 Magna Cum Laude in Biochemistry, Princeton University 
1980-81 Rotary International Foundation Postgraduate Fellowship for the Humanities, 
University of Kent, England 
1984-85 Medical Student Research Training Award, National Institutes of Health 
1985 Henry Strong Denison Award for Medical Research 
1985 Warfield T. Longcope Prize for Excellence in Clinical Medicine 
1988-89 American Cancer Society Clinical Oncology Fellowship Award 
1990 Hecht Fund Award for Cancer Research 
1990-95 Physician Scientist Award, National Institutes of Health, National Cancer 
Institute, Award Number K11CA01495-02 
Publications 
■ 
1. Racker, E., Miyamato, H. , Mogerman, J., Simons, J.W., and O'Neil, S.N. Cation 
Transport in Reconstituted Systems. Ann. N.Y. Acad. Sci. 358 : 5-19 . 1980. 
2. Sandford, G.R., Wingard, J.R., Simons, J.W., Staal, S.P., Saral, R. , and Burns, 
W.H. Genetic Analysis of the Susceptibility of Mouse Cytomegalovirus to Acyclovir. 
J. Virol. 54 : 104 - 113 , 1985 . 
3 . Simons, J.W., Noga, S., Colombani, P.M., Beschorner, W.E., Coffey, D.S., and Hess, 
A.D. Cyclosporin A Induces Alterations in the Nuclear Morphology of Human 
Mononuclear Leukocytes. J, Cell Biochem. 125 - 136 , 1985 . 
PH<nVMVa*w 0/RA\ 
Re com bi nant DNA Re s earch, Volum e -4 3 
