PUBLICATIONS (Selected) 
1. Yoshimura K, Nakamura H, Trapnell BC, Dalmans W, Pavirani A, Lecocq J-P, and Crystal 
RG. The Cystic Fibrosis Gene Has A "Housekeeping" -Type Promoter And Is Expressed At Low 
Levels In Cells Of Epithelial Origin. J Biol Chem 266: 9140-9144, 1991. 
2. Chu C-S, Trapnell BC, Murtagh JJ, Moss J, Dalmans W, Pavirani A, Lecocq J-P, Cutting G, 
Guggino WB, and Crystal RG. Variable Deletion Of Exon 9 Coding Sequences in Cystic 
Fibrosis Transmembrane Conductance Regulator Gene mRNA Transcripts In Normal Bronchial 
Epithelium. EMBO 10: 1355-1363, 1991. 
3. Trapnell BC, Zeitlin PL, Chu CS, Yoshimura K, Nakamura H, Guggino WB, Bargon J, Banks 
TC, Dalmans W, Pavirani A, Lecocq J-P, and Crystal RG. Down regulation Of Cystic Fibrosis 
Gene mRNA Transcript Levels And Induction Of The Cystic Fibrosis Chloride Secretory 
Phenotype In Epithelial Cells By Phorbol Ester. J Biol Chem 266: 10319- 10323, 1991. 
4. Trapnell BC, Chu CS, Paako PK, Banks TC, Ferrans VJ, Chernick MS, and Crystal RG. 
Expression Of The Cystic Fibrosis Gene In The Respiratory Tract Of Normals And Individuals 
With Cystic Fibrosis. Proc Natl Acad Sci (USA) 88: 6565-6569, 1991. 
5. Hamosh A, Trapnell BC, Montrose-Ranzadeh C, Zeitlin PL, Rosenstein BJ, Crystal RG, and 
Cutting GR. Severe Deficiency of CFTR mRNA Carrying Nonsense Mutations R553X and 
W1316X in Respiratory Epithelia of Patients With Cystic Fibrosis. J Clin Invest 88:1880-5, 
1991. 
6. Rosenfeld MA, Yoshimura K, Trapnell BC, Yoneyama K, Rosenthal ER, Dalemans W, Bargon 
J, Stier LE, Stratford-Perricaudet L, Perricaudet M, Guggino WB, Pavirani A, Lecocq J-P, 
Crystal RG. In Vivo Transfer of the Human Cystic Fibrosis Transmembrane Conductance 
Regulator Gene to the Airway Epithelium. Cell 68:143-155, 1992. 
7. Chu C-S, Trapnell BC, Curristin SM, Cutting GR and Crystal RG. Extensive Post-Translational 
Deletion of the Coding Sequences for Part of Nucleotide Binding Fold-1 in Respiratory 
Epithelial mRNA Transcript? of the Cystic Fibrosis Transmembrane Conductance Regulator 
Gene is Not Associated With the Clinical Manifestations of Cystic Fibrosis. J Clin Invest 
90:785-90, 1992. 
8. Bargon J, Trapnell BC, Chu C-S, Rosenthal ER, Yoshimura K, Guggino WB, Dalemans W, 
Pavirani A, Lecocq J-P, and Crystal RG. Down-Regulation of Cystic Fibrosis Transmembrane 
Conductance Regulator Gene Expression by Agents That Modulate Intracellular Divalent 
Cations. Mol Cell Biol 12:1872-8, 1992. 
9. Chu C-S, Trapnell BC, Curristin S, Cutting GR, and Crystal RG. Genetic Basis for Variable 
Exon 9 Skipping in Cystic Fibrosis Transmembrane Conductance Regulator mRNA. Nature 
Genetics (In Press) 
10. Trapnell BC. Quantitative Evaluation of Gene Expression in Human Respiratory Epithelial 
Cells. Am J Physiol (In Press). 
11. Nakamura H, Yoshimura K, Bajocchi G, Trapnell BC, Pavirani A and Crystal RG. Tumor 
Necrosis Factor Modulation of Expression of the Cystic Fibrosis Transmembrane Conductance 
Regulator Gene. FEBS 314: 366-70. 
[4301 
Recombinant DNA Research, Volume 17 
