The virus we are using does not cause any known disease in 
human beings and has been altered so that it cannot replicate 
itself once it is placed into your body via the bone marrow 
cells. No side effects have been seen in over 50 patients that 
have received cells treated with this type of virus, although no 
patients prior to this study have received cells treated with the 
GC virus. 
One important theoretical risk is the possible development 
of cancer. It is theoretically possible that the virus that is 
put into your bone marrow cells could cause the development of 
cancer in your body. The development of cancer has not been 
observed in any of the animals or patients treated with this type 
of virus. It is our opinion that the risk of developing a cancer 
as a result of this treatment is extremely low. 
As in any new form of therapy, there may be risks which are 
unknown or not anticipated. Because we will only be putting the 
new GC gene into your bone marrow cells, we do not anticipate 
that it can be passed on to any children you may have in the 
future. Participating in this study will not lower the risk of 
passing Gaucher Disease to your offspring. 
PHYSICAL INJURY 
The possible risks associated with this study plan have been 
presented. There is always the possibility that physical injury 
may occur. The Childrens Hospital Los Angeles maintains 
professional liability insurance to protect patients from 
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