APPENDIX A TO APPENDIX C 
Award of New and Competing Renewal Project s 
Prior to the award of any project involving recombinant DMA 
technology, the NIH awarding component will forward to ORDA 
one copy of each of the following documents; the application, 
summary statement, MUA, Certification, any comments of the 
final review body, and a request for clearance to award. In 
those cases in which the initial or final review group, or 
staff of an awarding BID finds that a project requires a higher 
level of containment than that originally proposed by the appli- 
cant or the institution, a properly executed revised MUA and 
Certification Statement will be required prior to a request 
for approval to award. ORDA will review the documents and 
indicate concurrence or non-concurrence with the request for 
clearance to award. In the latter' case, ORDA will prepare a 
memorandum outlining the reasons for disapproval but emphasizing 
that the action is independent of scientific merit or other 
reasons. Such a memorandum should be forwarded to the applicant 
through the av^arding unit. In those cases in v;hich ORDA is not 
able to reach a decision, or in which the awarding component 
or applicant disputes the decision, the decision will be sub- 
mitted to the Executive Coimiittee , and, if necessary, to the 
Recombinant Advisory Committee, for reviev/. The final decision 
will rest with the Deputy Director for Science, NIH. 
BIDS will forward to ORDA a copy of all aw^'d statements in- 
volving these applications. 
ORDA will retain in its files the documents cited above. In 
the event that the volume of filed documents becomes excessive, 
ORDA will retain a copy of the face sheet of a funded application 
rather than the entire application. In those cases in which the 
proposed project involving recombinant DNA technology is but one 
component of a multiproject application, ORDA will retain in its 
files the face sheet of the application and the section(s) de- 
scribing the project(s) involving recombinant DNA technology. 
It must be emphasized that the primary responsibility for ensuring 
that applications have been properly reviewed, and that required 
documents are properly executed lies with NIH staff involved with, 
the initial review groups and program areas. The procedures pro- 
posed above are intended to serve as a final review prior to award. 
ORDA will be available to NIH staff for advice and consultation, 
but it can not be expected to make decisions for review units 
and awarding components. 
Appendix C — 9 
