APPENDIX C TO APPENDIX C 
Transition and Implementation 
The procedures proposed in Appendices A and B should be implemented as 
soon as possible. However, clearly there v;ill be an interim period after 
the Guidelines are issued and before all the procedures are functioning. 
It is the purpose of this Appendix to propose how the Office of Recom- 
binant I^A Activities (ORDA) might initiate coordination and gathering 
of information during this period. 
I. Intramural Research 
ORDA will brief the Scientific Directors of the BIDs who will be 
expected to assure ORDA and the Deputy Director for Science, NIH 
of present and future compliance by intramural research scientists 
with the Guidelines. 
ORDA will request the Deputy Director for Science, NIH to provide 
a copy of the final MUA on all intramural projects, utilizing re- 
comingant ENA technology, which are already in progress. After 
review of the MUAs, ORDA will report any concerns to the Deputy 
Director for Science, NIH. 
II. Extramural Programs 
ORDA will brief the Executive Committee for Extramural Affairs 
on NIH policies and procedures. 
BIDS will be required to report to ORDA all present or planned 
workshops, training courses, conferences, etc., relating to re- 
combinant DNA technology. BIDS must also report all present or 
planned P^FPs and RFAs likely to result in projects utilizing re- 
combinant DNA technology. After review of this information, 
ORDA will report any concerns to the Deputy Director for Science, 
NIH and/or the Executive Committee. 
With regard to active grants and contracts, BIDs will be required 
to submit to ORDA a copy of the application, summary statement and 
award statement for each currently funded project involving recom- 
binant DNA technology. NIH awarding components will be responsible 
for ensuring that this reporting is as coitplete as possible. 
BIDS will send a letter to investigators identified in the para- 
graph above to determine whether active research projects are in 
Appendix C — 14 
