appendix j 
standards, (c) the licensing requirements prescribed in the legislation 
have been satisfied, and (d) the registration requirements prescribed 
in the legislation have been satisfied. 
The legislation should permit the Secretary to exempt activities 
from these requirements (a) where the activity is for specific commercial 
purposes found by the Secretary, after consultation with the regulating 
agency, to be regulated under other Federal law, or (b) where the Secretary 
determines that the activity poses no unreasonable risk to health or the 
environment . 
(3) Standards : 
The Secretary should be directed, as soon as practicable after passage 
of the legislation, to promulgate the NIH Guidelines for Research Involving 
Recombinant DNA Molecules as initial standards, with such clarifications 
and modifications as the Secretary determines to be necessary. Standards 
should assure, on the basis of the best currently available evidence, 
that no employee will suffer material impairment of health or functional 
capacity even if such employee engages in the production or use of recombinant 
DNA molecules for an entire working lifetime. 
The legislation should authorize the Secretary to modify and revoke 
any of these initial standards and to promulgate new standards. 
The legislation should include an appropriate provision for judicial 
review. 
Appendix J — 13 
