- 2 - 
sources and the possible environmental consequences 
of its escape. Although we recognize that everything 
presented in the draft is applicable to plant as well 
as animal and prokaryotic DNA, containment in research 
where the host cells are in whole plants presents dif- 
ferent problems than microbial or tissue culture 
research as stated in the guidelines. This matter should 
be addressed in the draft EIS. 
Sincerely yours, 
Edward P. Todd 
Deputy Assistant Director 
cc: BBS/Dr. Clark 
06C/Mr. Kusinski 
BBS/PCM/Dr. Lewis 
Appendix K — 79 
