containment requirements and to limit the number of 
facilities where recombinant research can be conducted. 
Laboratory workers should be licensed to ensure that they 
are properly trained. The NIH grantee should be required 
to conduct and report regular epidemiological studies on its 
workers. The Guidelines should be revised to eliminate or 
simplify the factual determinations which have to be made by 
the staff. Finally, the regulations should include strong 
sanctions: criminal penalties for intentional or negligent 
release of recombinant organisms; license and grant revocation 
for lesser violations. 
Attachments 
1. 
George Wald, "The Case Against Genetic 
September/October 1976 (12 pages). 
Engineering , 
" The Sciences 
2. 
Janice Crossland, "Hands on the Code," 
No. 7, September 1976 (10 pages). 
Environment , 
Vol. 18, 
27 
Appendix K — 153 
