Recombinant DNA Advisory Committee - 3/3-4/94 
Dr. Parkman said that the RAC should continue to solicit ad hoc experts who could 
provide relevant presentations regarding inadvertent germ-line transmission. Such 
presentations would represent a continuation of series of educational presentations on 
the issue of germ-line gene transfer. With the advent of genetic science, the 
development of the framework and policy for reviewing such protocols is important. Dr. 
Walters said that it is an excellent suggestion and the Institute of Medicine of the 
National Academy of Sciences is proposing to initiate a formal study on gene 
intervention in germ-line cells. Dr. Post said that the immediate likelihood of the RAC 
to encounter this problem is the inadvertent germ-line modification in gene transfer 
studies. 
Dr. Walters stated that Dr. Harold Varmus, NIH Director, has indicated his intention to 
attend the September 1994 RAC meeting. 
XX. ADJOURNMENT 
Dr. Walters adjourned the meeting at 2:32 p.m. on March 4, 1994. 
Executive Secretary 
I hereby acknowledge that, to the best of my 
knowledge, the foregoing Minutes and Attach- 
ments are accurate and complete. 
Chair 
Recombinant DNA Advisory Committee 
National Institutes of Health 
[641 
Recombinant DNA Research, Volume 19 
