FF Principal Investigator/Program Director (Last, first, middle): 
TT) Ohashi, T„ Boggs, S., Robbins, P., Bahnson, A., Patrene, K., Wei, F.-S., Wei, J.-K, Fei, Y., Li, J 
Luchl, L., Clark, S., Kimak, M., He, H., Mowery, P., and J. A. Barranger. (1992) Efficient’ 
transfer and sustained high expression of the human glucocerebrosidase gene in mice and their 
functional macrophages following transplantation of bone marrow transduced by a retroviral vector 
Proc. Natl. Acad. Sci. USA 89:11332-11336 
12) Bandara, G., Robbins, PD., Georgescu, HI., Glorioso, JC., and Evans, CH. (1992) Gene transfer to 
synoviocytes: Prospects for gene treatment for arthritis. DMA Cell. Biol. 11:227-231 
13) Evans, C. H., Bandara, G., Robbins, P.D., Mueller, G., and J. C. Glorioso. (1993) The future of gene 
therapy and rheumatic diseases, in The Molecular Basis of Medicine. Eds. C. V. Chang and A. M 
Feldman, Mosby-Year Book, Inc. in press. 
14) Evans, C. H., Bandara, G., Robbins, P.D., Mueller, G., Georgescu, H. I., and J. C. Glorioso. (1993) 
Gene Therapy for Ligament Healing, in Anterior Crucia Ligament - Current and Future Concepts. 
Eds. S. Amoczky, S.L.Y. Woo, C. B. Frank, and D. W. Jackson. Raven Press, pgs. 419-422. 
15) Robbins, P.D. and S. A. Khan. (1992) Review of In Focus: DNA Replication by R. 1. P. Adams for 
the Quarterly Review of Biology 67:354. 
16) Ohtani-Fujita, N., Fujita, T., Aoike, A., Osifchin, N., Robbins, P.D., and T. Sakai. CpG methylation 
inactivates the promoter activity of the human retinoblastoma tumor- suppressor gene. Oncogene 
8:1063-1067. 
17) Jiang, D., Srinivasan, A., Lozano, G., and P. D. Robbins. SV40 T-antigen abrogates p53-mediated 
transcriptional activity. Oncogene 8:2805-2812. 
18) Bandara, G., Mueller, G. M., Galea-Lauri, J., Tyndall, M. H., Georgescu, H. I., Suchanek, M. K., 
Hung, G. L., Glorioso, J. C., Robbins, P. D., and C. H. Evans. Intraarticular expression of the 
interleukin- 1 receptor antagonist protein by ex- vivo gene transfer. Proc. Natl. Acad. Sci 90:10764- 
10768. 
19) Bahnson, A., Nimgaonkar, M., Boggs, S. S., Robbins, P. D., Patrene, K., Fei, Y., Li, J., Ball, T., 
and J. A. Barranger (1993) Transduction and expression of the human glucocerbrosidase gene in the 
long term murine model and in rhesus monkey bone marrow and human CD34 cells. Proc. of the 
Sixth International Symposium on Autologous Bone Marrow Transplantation, pgs. 138-144, K. 
Dickie and A. Keating, Eds. Baylor College of Medicine Press. 
20) Evans, C. H. and P. D. Robbins. (1993) Gene therapy for arthritis in Direct Gene Therapy, ed. J. A. 
Wolff, Birkhause press, in the press. 
21) Evans, C. H. and P. D. Robbins (1993) The interleukin-1 receptor antagonist and its delivery by gene 
transfer. Receptor, in the press. 
22) Robbins, P. D., Tahara, H., Mueller, G. M., Hung, G., Bahnson, A., Zitvogel, L., Galea-Lauri, J., 
Ohashi, T., Patrene, K., Boggs, S. S., Evans, C. H., Barranger, J. A., and M. T. Lotze. (1993) 
Retroviral vectors for use in human gene therapy for cancer, Gaucher disease, and arthritis. Annals of 
the New York Academy of Sciences, in the press 
23) Evans, C. H. and P. D. Robbins (1993) Gene Therapy for Arthritis. J. Rheumat., in press. 
24) Calmels, T,, Mistry, J. L., Watkins, S., Robbins, P. D., McGuire, R., and J. S. Lazo. Nuclear 
localization of the bacterial Sh-Ble protein in mammalian cells. Mol. Pharm.^:\\2>5-\\A\ 
25) Hung, G. L., Bandara, G., Galea-Lauri, J., Mueller, G. M., Georgescu, H. L, Larkin, L. A.,Tyndall, 
M. H., Robbins, P. D., and C. H. Evans. Suppression of intraarticular response to interleukin-1 by 
gene transfer to synovium. Gene Therapyl:(A-69 
26) Tahara, H., Zeh, H. Ill, Storkus, W. J., Hurd, S., Pappo, L, Gately, M. K., Gubler, U., Wolf, S. F., 
Robbins, P. D., and M. T. Lotze. Decreased tumor growth with local secretion of interleukin- 12 
delivered by transfected fibroblasts. Can. /?e5'.54: 182- 189. 
27) Bahnson, A. B., Nimgaonkar, M., Fei, Y., Boggs, S. S., Robbins, P. D., Ohashi, T., Dunigan, J., Li, 
J., Ball., E. D., and J. A Barranger. Transduction of CD34-F enriched cod blood and Gaucher bone 
marrow cells by a retroviral vector carrying the glucocerebrosidase gene. Gene Therapy, in press. 
28) Hung, G., Robbins, P. D., and C. H. Evans, Synovial Cell Transplantation in Cell Transplantation, J. 
C. Glorioso, Ed., in press 
29) Osifchin, N., Fujita, T., Aoike, A., Kim, S.-J., Sakai, T., and P. D. Robbins. p53 can postively 
regulate the retinoblastoma susceptiblity gene promoter in CCL-64 cells through a specific DNA 
sequence. J. Biol. Chem, in press 
30) Boggs, S. S., Mueller, G. M., Patrene, K., Evans, C. H., and P. D. Robbins. Expression and 
biological activity of IL-1 receptor antagonist in the bone marrow of long-term reconstituted mice, in 
preparation 
Recombinant DNA Research, Volume 19 
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