FF 
Prifxapal Investigatof/Pfogram Director (Last first, mkfdh): 
Champlin, Richard E. 
BIOGRAPHICAL SKETCH 
Give the (dlowirtg biformation for the key persorvtel and cortsuitants and coOaborators. Begin with the principal 
investigator/progra/n director. Photocopy this page for each person. 
NAME 
POSITION Tm.£ 
Richard E. Champlin, M.D. 
Professor of Medicine 
EDUCATION (Begin with bacxalaureate or other initia! professional education, soch as nursing, and indude postdoctoral training.) 
INSTITUTION AND LOCATION 
DEGREE 
YEAR 
CONFERRED 
RELD OF STUDY 
Purdue University, Indiana 
B.S. 
1971 
Engineering Science 
University of Chicago, Illinois 
M.D. 
1975 
Medicine 
RESEARCH AND PROFESSIONAL EXPERIENCE: Concluding with present position, Est in chronological order, previous emptoymerrt, experience, and 
honors. Key personnel indude the principal investigator and any other individuals who participate in the sdentific devetopmerrt or execution of the project 
Key person;^ typicaDy will indude aB individuals with doctoral or other professional degrees, but in some projects will irtdude irx£vidual$ at the masters or 
baccalaureate l^el provided they contribute in a substantive way to the sdentific development or execution of the project Inciude present membership on 
any Federal Government public advisory committee. List in chronotogical order, the titles, all authors, and complete references to al pubCcalions during the 
past three years and to representative earter pubOcalions pertinent to this appficatioa DO NOT EXCEED TWO PAGES. 
EMPLOYMENT : 
1975-1978 UCLA Harbor General Hospital, Internship and Residency in Medicine 
1978-1981 UCLA Center for the Health Sciences 
Fellowship in Hematology and Oncology 
1981-1985 Assistant Professor of Medicine, UCLA School of Medicine 
1985-1990 Associate Professor of Medicine, UCLA School of Medicine 
1983-1990 Director, Transplantation Biology Program 
UCLA Johnsson Comprehensive Cancer Center 
1985-1990 Director, UCLA Hematology/Oncology Fellowship Program 
1990-present Professor of Medicine, University of Texas, M.D. Anderson Cancer Center 
Chief, Section of Bone Marrow Transplantation 
1990-present President, Council of Donor Transplant and Collection Centers, National Marrow Donor Program 
1990- present Member of Executive Board of Directors, International Bone Marrow Transplant Registry 
1991 - present Consulting Staff, The Methodist Hospital, Internal Medicine and Hematology/Oncology 
PUBLICATIONS : 
1. Champlin RE . Gale RP. Acute lymphoblastic leukemia: recent advances in biology and therapy. Blood 
1989; 73:2051-2066. 
2. Sawyers CL, Timson L, Kawasaki ES, Clark SS, Witte ON, Champlin R . Molecular relapse in chronic 
myelogenous leukemia patients after bone marrow transplantation detected by polymerase chain reaction. 
Proc Natl Acad Sci USA. 1990;87:563-567. 
3. Champlin RE . Nimer SD, Ireland P, Oette DH, Golde DW. Treatment of ref ractory aplastic anemia with 
recombinant human granulocyte-macrophage colony-stimulating factor. Blood 1989; 73:694-699. 
4. Champlin R . T-cell depletion to prevent graft-versus-host disease after bone marrow transplantation. 
Hematol Oncol Clin North Am. 1990;4:687-698. 
5. Gajewski J, Ho WG, Nimer S, Hirji KF, Jacobs A, Champlin RE . Efficacy of intensive chemotherapy 
for acute myelogenous leukemia associated with a preleukemic syndrome. J Clin Oncol 1989; 
7:1637-1645. 
6. Gajewski JL, Ho WG, Feig SA, Hunt L, Kaufman N, Champlin RE . Bone marrow transplantation using 
unrelated donors for patients with advanced leukemia or bone marrow failure. Transplantation 1990; 
50:244-249. 
7. Champlin RE . Ho WG, Gajewski J, Feig S, Burnison M, Holley G, Greenberg P, Lee K, Schmid I, 
Giorgi J, Yam P, Petz L, Winston D, Warner N, Reichert T. Selective depletion of CD8 positive 
T-lymphocytes for prevention of graft-versus-host disease following allogeneic bone marrow 
transplantation. Blood 1990; 76:418-423. 
Recombinant DNA Research, Volume 19 
[545] 
