3.0 Treatment And Monitoring Schema 
The treatment and monitoring schedules are summarized in Figures 5 and 6. After each injection, 
patients will be contacted daily for 3 days to determine if the injection site is swollen or red. If a history 
of any erythema or induration is elicited, then the patient will be examined within 24 hours. All subjects 
will be examined 14 days after each immunization. Physical examinations and laboratory evaluations will 
be performed every two weeks during the first 8 weeks of the study, once a month for three months and 
every 3 months for one year after the completion of therapy and at least yearly thereafter. 
Figure 5 Treatment and Monitoring Summary 
Day - 60 Tumor biopsies 
Genetic modification of tumor cells 
Days + 0, 14,28 Immunization with irradiated transduced 
tumor cells 
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