Attachnait EL - FSge 1 
8810-001* 
9007-002*' b 
9007-003* 
9102-004* 
9105-005* 
9105-006* 
9105-007* 
C 
HUMAN GENE TRANSFER PROTOCOLS 
(M) Rosenberg, Steven A.; National Institutes of Health, Bethesda, Maryland; The Treatment of Patients with 
Advanced Cancer Using Cyclophosphamide, Interleukin-2 and Tumor Infiltrating Lymphocytes. 
RAC Approval: 10-3-88/NIH Approval: 3-2-89 ■ 
Minor Modification: 3-30-90 
(T) Blaese, R. Michael; National Institutes of Health, Bethesda, Maryland; Treatment of Severe Combined 
Immune Deficiency (SCID) due to Adenosine Deaminase (ADA) Deficiency with Autologous Lymphocytes 
Transduced with the Human ADA Gene : An Experimental Study 
RAC Approval: 7-31-90/NIH Approval: 9-6-90 
Major Amendment/RAC Approval: 2-10-92 
Major Amendment/NIH Approval: 4-22-92 
Minor Modification: 4-21-93 
Minor Modification: 6-7-93 > 
(T) Rosenberg, Steven A.; National Institutes of Health, Bethesda, Maryland; Gene Therapy of Patients with 
Advanced Cancer Using Tumor Infiltrating Lymphocytes Transduced with the Gene Coding for Tumor 
Necrosis Factor. 5 
RAC Approval: 7-31-90/NIH Approval: 9-6-90 
Minor Modification: 2-17-94 
(M) Brenner, Malcolm K.; Mirro, Joseph; Hurwitz, Craig; Santana, Victor; and Ihle, James; St. Jude 
Children’s Research Hospital, Memphis, Tennessee; Autologous Bone Marrow Transplant for Children with 
Acute Myelogenous Leukemia in First Complete Remission: Use of Marker Genes to Investigate the Biology 
of Marrow Reconstitution and the Mechanism of Relapse. 
RAC Approval: 2-4-91/NIH Approval: 7-12-91 
Minor Modification: 11-91 
CLOSED: 1-15-93 
(M) Brenner, Malcolm K.; Mirro, Joseph; Santana, Victor; and Ihle, James; St. Jude Children’s Research 
Hospital, Memphis, Tennessee; A Phase I/II Trial of High Dose Carboplatin and Etoposide with Autologous 
Marrow Support for Treatment of Stage D Neuroblastoma in First Remission: Use of Marker Genes to 
Investigate the Biology of Marrow Reconstitution and the Mechanism of Relapse. 
RAC Approval: 5-31-91/NIH Approval: 7-12-91 
Minor Modification: 11-91 > 
CLOSED: 6-1-92 
(M) 
Brenner Malcolm K.; Mirro, Joseph; Santana, Victor; and Ihle, James; St. Jude Children’s Research 
Hospital, Memphis, Tennessee; A Phase II Trial of High-Dose Carboplatin and Etoposide with Autologous 
YnZZment P ° n ” ^ °f Rela P se / R ^tory Neuroblastoma Without Apparent Bone Marrow 
RAC Approval: 5-31-91/NIH Approval: 7-12-91 
Minor Modification: 11-91 
CLOSED: 4-9-93 
(M) 
Trans Dlant 'aZZfn ^ !^ /^ n ^ erson < “‘ ancer Research Center, Houston, Texas; Autologous Bone Marrow 
bZZn rZTJ. ifiOT' y ' ,oge " ou3 hernia in which Retroviral Markers are Usedto Discriminate 
,o ReZuln V Remaining after Preparative Therapy Versus Relapse due 
to Residual Leukemic Cells in Autologous Marrow: A Pilot Trial 
RAC Approval: 5-31-91/NIH Approval: 7-12-91 
Minor Modification: 4-19-93 
CLOSED: 6-1-93 
[92] 
Recombinant DNA Research, Volume 20 
