Attachment II - F^ge 8 
9312-065 
9312-066 
9312 - 067 3 
9403 - 068 * 
9403-069 
9403-070 
9403-071 
9403-072 
9406-073 
9406-074 
9406-075 
9406-076 
(T) Chang, Alfred E.; University of Michigan, Ann Arbor, Michigan; Adoptive Immunotherapy of Melanoma 
with Activated Lymph Node Cells Primed In Vivo with Autologous Tumor Cells Transduced with the IL~4 
Gene. 
RAC Approval: 12-3-93/N1H Approval: 8-93-24 
CO Sorscher . Eric J. and Logan, James L.; University of Alabama. Birmingham. Alabama: Gene Therapy for 
Cystic Fibrosis Using Cationic Liposome Mediated Gene Transfer A Phase I Trial of Safety and Efficacy in 
the Nasal Airway. 
RAC Approval: 12-3-93/NTH Approval: Pending 
(T) Welsh, Michael J.; Howard Hughes Medical Institute, Iowa City, Iowa; Adenovirus-Mediated Gene Transfer 
of CFTR to the Nasal Epithelium and Maxillary Sinus of Patients with Cystic Fibrosis. 
RAC Approval: 12-3-93/NIH Approval: 2-10-94 
Minor Modification: 2-17-94 
CO Rosenblatt, Joseph; University of California. Los Angeles, California: Seeger. Robert. Childrens Hospital. 
Los Angeles, California, and Merchant. Bruce, Viagene. Inc.. San Diego. California: A Phase I Study of 
Immunization with Gamma Interferon Transduced Neuroblastoma Cells. 
RAC Approval: 3-3-94/NTH Approval: Pending 
Minor Modification: 7-11-94 
(T) Walker, Robert; NIH, Bethesda, Maryland; A Phase I/II Pilot Study of the Safety of the Adoptive Transfer 
of Syngeneic Gene-Modified Cytotoxic T-Lymphocytes in HIV-Infected Identical Twins. 
RAC Approval: 3-3-94/NIH Approval: 8-23-94 
(T) Brigham. Kenneth; Vanderbilt University. Nashville. Tennessee: Expression of an Exogenously Administered 
Human Alpha- 1-Antitrypsin Gene in the Respiratory Tract of Humans. 
RAC Approval: 3-3-94/NIH Approval: Pending 
(T) Vogelzang, Nicholas; the University of Chicago, Chicago, Illinois; Phase I Study of Immunotherapy for 
Metastatic Renal Cell Carcinoma by Direct Gene Transfer into Metastatic Lesions. 
RAC Approval: 3-4-94/NIH Approval: 4-19-94 
(T) Hersh, Evan; Arizona Cancer Center, Tuscon, Arizona; and Akporiaye; Harris; Stopeck; Unger; and 
Warneke; the University of Arizona, Tuscon, Arizona; Phase I Study of Immunotherapy of Malignant 
Melanoma by Direct Gene Transfer. 
RAC Approval: 3-4-94/NIH Approval: 4-19-94 
(T) Curiel. David: University of Alabama. Birmingham. Alabama: Phase I Trial of a Polynucleotide Augmented 
Anti-tumor Immunization to Human Carcinoembryonic Antigen in Patients with Metastatic Colorectal Cancer. 
RAC Approval: 6-9-94/NIH Approval: Pending 
(T) Evans. C. H. and Robbins. Paul: University of Pittsburgh. Pittsburgh. Pennsylvania: Clinical Trial to Assess 
the Safety. Feasibility, and Efficacy of Transferrins a Potentially Anti-arthritic Cytokine Gene to Human Joints 
with Rheumatoid Arthritis. 
RAC Approval: 6-9-94/NIH Approval: Pending 
(M) Freedman, Ralph; MD Anderson Cancer Center, Houston, Texas; Use of a Retroviral Vector to Study the 
Trafficking Patterns of Purified Ovarian TIL Populations Used in Intraperitoneal Adoptive Immunotherapy of 
Ovarian Cancer Patients: A Pilot Study. 
RAC Approval: 6-9-94/NIH Approval: 7-12-94 
(M) Heslop, Helen; Brenner, Malcolm, K.; and Krance, Robert; St. Jude Childrens Research Hospital, 
Memphis, Tennessee; Use of Double Marking with Retroviral Vectors to Determine the Rate of Reconstitution 
of Untreated and Cytokine Expanded CD34( + ) Selected Marrow Cells in Patients Undergoing Autologous 
Bone Marrow Transplantation. 
RAC Approval: 6-9-94/NIH Approval: 7-12-94 
Recombinant DNA Research, Volume 20 
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