CONTINUATION PAGE: S'. WITHIN MARGINS INDICATED 
Principal Investigator/Program Director (Last, first, middle):. 
6. Schwiebert E, Fiotta TR, Cutting G, Guggino WB. CFTR and outwardly rectifying 
chloride channels contribute to whole cell chloride currents in normal airway epithelial 
cells are defectively regulated in cystic fibrosis. American Journal of. PhY?iQlOtTY 1994; 
266 ( Cell Phvs . 35) :C1464-1477 . 
7. Fiotte TR, Johns D, Loughlin GM. Neonatal apnea with autonomic dysfunction and anemia 
(AAA) : a new clinical triad associated with an inherited mitochondrial defect (submitted 
for publication) . 
8. Tomares S, Fiotte T, Tunkel D, Pao M, Loughlin GM. Real time laryngoscopy with 
olfactory challenge for diagnosis of psychogenic stridor. Pediatric puImon 0 lQ£T£ 1993; 
16:259-262. 
9. Fiotte TR, Solow R, Owens RA, Afione S, Zeitlin PL, Carter B J . Gene expression from 
adeno-associated virus vectors in airway epithelial cells. American Journal Ql. 
Respiratory £gll Mol ec ular Bi p l pg y 1992; 7:349-356. _ . 
10. Fiotte TR, Loughlin GM. Benefits and complications of troleandomycin (TAO) in young 
children with steroid-dependent asthma. Pediatric Pulmonology 1991; 10:178-182. 
Book Chapter 
1. Rosenstein BJ and Fiotte TR. 'New directions in treatment" (118 refs.) in CurTPDf. 
topics in cvstic fibrosis: Volume 1. Edited by J.D. Dodge, D.J.H. Brock, J.W. Widdicombe. 
1993, John Wiley & Sons, Chichester. 
Abstracts 
1. Fiotte TR, Conrad C, Afione SA, Solow R, Zeitlin PL, Guggino WB, Carter BJ . Stable 
in vivo CFTR gene expression from an AAV vector. Pediatric Pulmonology 1993; S9:74-75. 
2. Fiotte TR. AAV vectors in the human airway: Integration, immunity and vector rescue. 
Pediatric Pulmonology 1993; S9:182-183. 
3. Conrad C, Zeitlin P, Carter B, Guggino W, Fiotte T. Immunodetection of epitope-tagged 
CFTR after in vivo gene transfer with an AAV vector. Pediatric Pulmonology 1993; S9:242. 
4. Kearns W, Afione S, Cutting G, Carter B, Pearson P, Fiotte T. AAV -CFTR vectors 
integrate at multiple' chromosomal sites in a CF bronchial epithelial cell line. Pe<3ifltri£ 
Pulmonology 1993; S9:242. 
5. Zeitlin P, McVeigh U, Conrad C, Fiotte TR, Guggino WB. Neonatal gene therapy for 
cystic fibrosis. Pediatric Pulmonology 1993 (in press). 
6. Schwiebert E, Kiesewetter S, Fiotte TR, Stanton B, Cutting G, Guggino WB. Both 
outwardly directed chloride channels (ORCC) and CFTR chloride channels contribute to cAMP- 
activated chloride currents in normal airway epithelial cells and in CF cells transduced 
with AAV-CFTR. Pediatric Pulmonology 1993; S9 : 224. 
7. Piazza-Carroll T, Schwiebert E, Fiotte TR, Guggino WB. The N-terminus of CFTR and the 
first transmembrane segment of TM domain 1 are not essential for chloride channel function 
of CFTR. Pediatric Pulmonology 1993 (in press) . 
8. Fiotte TR, Afione SA, Solow R-, Conrad C, McGrath SA, Zeitlin PL, Guggino WB, Carter 
BJ. In vivo gene transfer with adeno-associated virus vectors. American Review o£ 
Respiratory Disease 1993; 147:A544. 
9. Zuckerberg A, Martin L, Fiotte TR, Cooper PD, McMillan J, Flick RP, Nichols DG. An 
alternative method of ribavirin administration to the non-intubated infant. Presented at 
1993 American Society of Critical Care Medicine (Pediatrics) meeting. 
10. Zuckerberg A, Fiotte TR, Martin LD. The use of ribavirin in mechanically ventilated 
patients with chronic lung disease. American Review of Respiratory Disease 1993; 
147 : A133 . 
11. Fiotte T, Solow R, Afione SA, Conrad C, Zeitlin PL, Carter B J . In vivo CFTR gene 
transfer with adeno-associated virus vectors. Pediatric Pulmonology 1992; 14:263. 
12. Fiotte T, Afione S, Solow R, Carter B. Expression of CFTR from AAV vectors. 
Pediatric Pulmonology 1992; S8:237. 
13. Egan ME, Fiotte TR, Zeitlin PL, Carter B, Guggino WB. Correction of defective 
regulation of outwardly rectifying Cl' channels in CF airway epithelial cells after 
insertion of the normal cystic fibrosis transmembrane regulator. Pediatric Pulm onology 
1992; S8 : 254 . 1 
14. Fiotte TR, Zeitlin P, Afione S, Solow R, Druram M, Guggino W, Carter BJ. 
Complementation of the CF defect in bronchial epithelial cells using an AAV vector: CFTR 
expression and restoration of forskolin-stimulated chloride efflux. Pediatric P 1 i1m < r >noloqV - 
1991; Sup. 6:247. 
15. Fiotte TR, Zeitlin P, Afione S, Solow R, Guggino W, Carter BJ. Intracellular 
localization of CFTR expressed from an AAV vector in CF airway epithelial cells. 
Pulmonology 1991; Supplement 6:247. . 
16. Carter B, Fiotte TR, Zeitlin P, Solow R, Owens R, Afione S, Drumm M, Guggino W. 
Adeno-associated virus vectors and complementation of cystic fibrosis. Pf^i ^ trie 
Pulmonology 1991; Supplement 6:187-188. 
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Recombinant DNA Research, Volume 20 
