FF 
Principal Investigalor/Program Oireclor (Last, tirsl, middle): Cie/Stal , Ronald G. 
8 - 
BIOGRAPHICAL SKETCH 
Give (he following information (or (he key personnel and consultants and collaborators. Begin with the principal 
investigalor/program director. Photocopy this page lor each person. 
CVs 
name position title 
Prof, of Med, Chief, Div. Pulm. &Crit. Care Med, 
Ronald G. Crystal The New York Hospital -Cornell Med. Center 
EDUCATION (Begin with baccalaureate or other initial professional education, such as nursing and include postdoctoral (raining.) 
INSTITUTION ANO LOCATION 
DEGREE 
YEAR 
CONFERRED 
FIELD OF STUDY 
Tufts University, Medford, Massachusetts 
B.A. 
1962 
Physics 
University of Pennsylvania, Philadelphia, PA 
M.S. 
1963 
Physics 
University of Pennsylvania, Philadelphia, PA 
M.D. 
1968 
Medicine 
RESEARCH AND PROFESSIONAL EXPERIENCE: Concluding with present position, list, in chronological order, previous employment, experience, and 
honors. Key personnel indude the prindpa! investigator and any other individuals who parlidpale in the sdenlific development or execution of the projed. 
Key personnel typically will indude aH individuals with doctoral or other professional degrees, but in some projects will indude individuals at the masters or 
baccalaureate level provided they contribute in a substantive way to the sdenlific development or execution of the projed. Indude present membership on 
any Federal Government public advisory committee. List, in chronological order, the titles, all authors, and complete references to all publications during the 
past three years and to representative earfier publications pertinent to this application. If the fist of publications in the last three years exceeds two pages, 
seled the most pertinent publications. DO NOT EXCEED TWO PAGES. 
Professional Training and Experience 
1968 - 1970 Intern & Resident in Medicine, Massachusetts General Hospital, Boston, Massachusetts 
1970 - 1972 Research Associate, Section on Molecular Hematology, NHLI, NIH, Bethesda, Maryland 
1972 - 1975 Head, Section on Pulmonary Biochemistry, NHLI, NIH, Bethesda, Maryland 
1973 Clinical Fellow, Chest Medicine, University of California, San Francisco 
1975 - 1993 Chief, Pulmonary Branch, NHLBI, NIH, Bethesda, Maryland 
1993 - present Special Volunteer, Pulmonary Branch, NHLBI, NIH, Bethesda, Maryland 
1993 - present Bruce Webster Professor of Medicine, Cornell University Medical College, New York, 
New York 
1993 - present Attending Physician, The New York Hospital, New York, New York 
1993 - present Chief, Division of Pulmonary and Critical Care Medicine, The New York Hospital- 
Comell Medical Center, New York, New York 
1993 - present Adjunct Professor, The Rockefeller University, New York, New York 
Military 
1970 - 1974, Surgeon, Commissioned Corps, USPHS; 1974 - 1979, Senior Surgeon, Commissioned Corps, 
USPHS; 1979 - 1993, Medical Director, Commissioned Corps, USPHS 
Board Certification 
1969, Diplomat of the National Board of Medical Examiners; 1974, Diplomat of the American Board of 
Internal Medicine; 1974, Diplomat in Pulmonary Disease, American Board of Internal Medicine 
Honors (selected) 
Elected member: Alpha Omega Alpha; American Society for Clinical Investigation; Association of 
American Physicians 
Awards: Public Health Service Commendation medal (1983), Outstanding Service medal (1988), 
Meritorious Service Award (1991) 
Honorary Degree: Doctor of Medicine, Johann Wolfgang Goethe University, Frankfurt, Germany (1992 
Publications (Selected from a list of 405) 
1. Garver RI, Chytil A, Courtney M, Crystal RG. Clonal gene therapy: transplanted mouse fibroblast lones 
express human al-antitrypsin gene in vivo . Science 1987; 237: 762-764. 
Recombinant DNA Research, Volume 20 
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