are taped to your chest to record the electrical activity of 
your heart; (4) an "echocardiogram" during which a microphone 
is moved across your chest to obtain a picture of your heart; 
and (5) a "chest X-ray" picture to see the outline of your 
heart . 
(6) MRI and bone X-rays At the end of the 1-year research period, 
we will also ask you to have an "MRI scan" of your head. For 
this test you would lie very still for approximately 1 hour in 
a closely-fitting machine which will obtain very clear pictures 
of your brain. We will also ask to obtain a series of X-ray 
pictures of your entire body to see the structure of your 
bones . 
(7) Avoid pregnancy Because gene therapy is new, we do not know if 
there will be any adverse effects on pregnancy or the fetus. 
We ask that you avoid pregnancy by using some form(s) of 
contraception during the 1-year treatment period of this 
research study. 
(8) Life-time follow-up Because gene therapy is very new, the 
long-term response and side-effects are not known. Therefore, 
we hope to stay in contact with you for your entire life-time. 
The research study described in this Consent Form will last for 
1 year only. However, we may ask you to have additional tests 
in the future. We also ask that you have an autopsy when you 
die so that we may learn more about your response to treatment 
and any possible side-effects. 
Risks and Benefits of Being in the Study: 
The study has several risks; 
(1) Some people having lymphocytes removed by the apheresis machine 
may have low blood pressure. A nurse or technician will watch 
for any changes in blood pressure while you are connected to 
the machine and will slow down the machine or stop the machine 
if blood pressure is too low. 
(2) Injection of your genetically modified lymphocytes may cause 
side-effects such as fever, chills, itching and rash, changes 
in blood pressure, or difficulty with breathing. To watch you 
closely for these possible side-effects, the first injections 
will be done on the Intensive Care Unit. If you have any of 
these reactions, the infusion of lymphocytes will be slowed 
down or stopped, and you may be given medications to treat 
these symptoms (such as hydrocortisone, Benedryl, or Tylenol) . 
If the first few injections go smoothly, the others will be 
given in a clinic or on a hospital ward instead of the 
Intensive Care Unit. 
(3) To genetically modify your lymphocytes, your blood cells will 
be treated in the laboratory with the L2SN virus which is 
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