198. Gal. D., Weir, L., Leclerc, G., Pickering, J.G., Hogan, J., Isner, J.M.: Direct myocardial transfection 
in two animal models: evaluation of parameters affecting gene expression and percutaneous gene delivery, 
.aboratory Investigation 68:18-25, 1993. 
.00. Isner, J.M., Rosenfield, K.R.: Redefining the treatment of peripheral artery disease. Role of 
percutaneous revascularization. Circulation 88:1534-1557, 1993 
205. Pickering, J.G., Weir, L., Jekanowski, J., Kearney M., Isner, J.M.: Proliferative activity in peripheral 
and coronary atherosclerotic plaque among patients undergoing percutaneous revascularization. Journal of 
Clinical Investigation 91:1469-1480, 1993. 
212. Isner, J.M., Kaufman, J., Rosenfield, K., Pieczek, A., Schainfeld, R., Ramaswamy, Kosowsky, 
B.D.: Combined physiologic and anatomic assessment of percutaneous revascularization using a Doppler 
guidewire and ultrasound catheter. American Journal of Cardiology 71:70D-86D, 1993. 
215. Takeshita, S., Gal, D., Leclerc, G., Pickering, J.G., Weir, L., Isner, J.M.: Increased efficiency of 
liposome-mediated arterial gene transfer associated with intimal smooth muscle cell proliferation following 
vascular injury. Journal of Clinical Investigation 93:652-661, 1994. 
216. Rosenfield, K., Isner, J.M.: Endovascular stents for iliac arterial disease. New England Journal of 
Medicine 329:620, 1993. 
217. Pickering, J.G., Jekanowski, J., Weir, L., Takeshita, S., Losordo, D.W., Isner, J.M.: Liposome- 
mediated gene transfer into human vascular smooth muscle cells. Circulation 89:13-21, 1994. 
218. Riessen, R., Rahimizadeh, H., Blessing, E., Takeshita, S., Barry, J.J., Isner, J.M.: Arterial gene 
transfer using pure DNA applied directly to hydrogel-coated angioplasty balloon. Human Gene Therapy 
4:749-758, 1993. 
222. Riessen, R., Isner, J.M.: Prospects for site-specific delivery of pharmacologic and molecular therapies. 
Journal of the American College of Cardiology 23:1234-1244, 1994. 
223. Isner, J.M., Pieczek, A., Rosenfield, K.: Untreated gangrene in patients with peripheral artery disease. 
Circulation 89:482-483, 1994. 
224. Takeshita, S., Zheng, L.P., Cheng, D., Riessen, R., Weir, L., Symes, J.F., Ferrara, N„ Isner, J.M.: 
Therapeutic angiogenesis following arterial gene transfer of vascular endothelial growth factor. (Submitted). 
225. Takeshita, S., Zheng, L.P., Brogi, E., Kearney, M., Asahara, T., Pu, L.Q., Bunting, S., Ferrara, N., 
ymes, J.F., Isner, J.M.: Therapeutic angiogenesis: a single intra-arterial bolus of vascular endothelial growth 
^actor augments revascularization in a rabbit ischemic hindlimb model. Journal of Clinical Investigation 
93:662-670, 1994. 
230. Losordo, D.W., Kearney, M., Isner, J.M.: Variable expression of the estrogen receptor in the normal 
and atherosclerotic coronary arteries. Circulation 89: 1501-1510, 1994. 
233. Isner, J.M.: Arterial gene therapy. Lancet (In Press). 
235. Losordo, D.W., Rosenfield, K., Kaufman, J., Piezcek, A., Isner, J.M.: Focal compensatory 
enlargement of human arteries in response to progressive atherosclerosis: in vivo documentation using 
intravascular ultrasound. Circulation (In Press). 
236. Steg, P.G., Feldman, L.J., Scoazec, J-Y., Tahlil, O., Barry, J.J., Boulechfar, S., Ragot, T., Isner, 
J.M., Perricaudet, M.: Site-specific arterial gene transfer to rabbit endothelial and smooth muscle cells using 
percutaneous delivery of an adenoviral vector. (Submitted). 
228. Takeshita, S„ Losordo, D.W., Kearney, M., Isner, J.M.: Time course of recombinant protein secretion 
following liposome-mediated gene transfer in a rabbit arterial organ culture model. Laboratory Investigation 
(In Press). 
229. Takeshita, S.T., Pu, L-Q., Zheng, L., Ferrara, N., Stein, L.A., Sniderman, A.D., Isner, J.M., Symes, 
J.F.: Vascular endothelial growth factor induces dose-dependent revascularization in a rabbit model of 
persistent limb ischemia. Circulation (In Press). 
239. Bauters, C., Asahara, T., Zheng, L.P., Takeshita, S., Bunting, S., Ferrara, N., Symes, J.F., Isner, 
J.M.: Physiologic assessment of angiogenesis induced by vascular endothelial growth factor in a rabbit 
ischemic hindlimb model. American Journal of Physiology (In Press). 
240. Brogi, E., Wu, T., Namiki, S., Isner, J.M.: Indirect angiogenic cytokines upregulate VEGF and bFGF 
gene expression in vascular smooth muscle cells, while hypoxia upregulates VEGF expression only. 
Circulation (In Press). 
245. Bauters C, Asahara T, Zheng LP, Takeshita S, Bunting S, Ferrara N, Symes JF, Isner JM: Site-specific 
lerapeutic angiogenesis following systemic administration of vascular endothelial growth factor. J Vase Surg 
v ln Press) 
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Recombinant DNA Research, Volume 20 
