Recombinant DNA Advisory Committee - 12/1-2/94 
XII. Addition to Appendix D of the NIH Guidelines Regarding a Human 
Gene Transfer Protocol Entitled; Gene Therapy of Primary and 
Metastatic Malignant Tumors of the Liver Using ACN53 Via 
Hepatic Artery Infusion : A Phase I Study/ Drs. Venook and Warren 35 
XIII. Addition to Appendix D of the NIH Guidelines Regarding a Human 
Gene Transfer Protocol Entitled; Phase I Study of Adenoviral 
Vector Delivery of the HSV-TK Gene and the Intravenous Administration 
of Ganciclovir in Adults with Malignant Tumors of the Central 
Nervous System /Drs. Grossman and Woo 41 
XTV. Proposed Amendments to Appendix B, Classification of Etiologic 
Agents and Oncogenic Viruses on the Bases of Hazard of the NIH 
Guidelines /Dr. Fleming 46 
XV. Presentation of Ethical Considerations Relative to In Utero 
Somatic Cell and Gene Therapies/Dr. Patterson 48 
XVI. Future Meetings of the RAC 52 
XVTI. Adjournment 52 
Attachment I: Roster 
Attachment II: Protocol List 
Attachment III: Minor Modifications 
Attachment IV: Data Management Report 
Attachment V: Acronyms 
Recombinant DNA Research, Volume 20 
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