Attad Trent II - Fcge 12 
9409-083 
9409-084 
9409-085 
9409-086 
9409-087 
9409-088 
9409-089 
9409-090 
9409-091 
(T/IGD/Cystic Fibrosis) 
Flotte, Terence R.; Johns Hopkins Childrens Center, Baltimore, Maryland; A Phase I Study of an 
Adeno-associated Virus-CFTR Gene Vector in Adult CF Patients with Mild Lung Disease. 
RAC Approval: 9-12-94/NIH Approval: 11-15-94 
(T/C/ Breast) 
Holt. Jeffrey, and Arteaga, Carlos B.: Vanderbilt University. Nashville. Tennessee; Gene Therapy for 
the Treatment of Metastatic Breast Cancer by In Vivo Infection with Breast-Targeted Retroviral Vectors 
Expressing Antisense c-fos or Antisense c-myc RNA. 
RAC Approval: 9-12-94/NTH Approval: Pending 
(T/IGD/Cystic Fibrosis) 
Crystal Ronald G.: New York Hospital-Cornell Medical Center. New York. New York: Evaluation 
of Repeat Administration of a Replication Deficient. Recombinant Adenovirus Containing the Normal 
Cvsn'c Fibrosis Transmembrane Conductance Regulator cDNA to the Airways of Individuals with Cvstic 
Fibrosis. 
RAC Approval: 9-12-94/NTH Approval: Pending 
(T/V/C/Breast) 
Lyerly, H. Kim; Duke University Medical Center, Durham, North Carolina; A Pilot Study of 
Autologous Human Interleukin-2'Gene Modified Tumor Cells in Patients with Refractory or Recurrent 
Metastatic Breast Cancer. 
RAC Approval: 9-12-94/NIH Approval: 10-25-94 
(T/IGD/Hunter Syndrome) 
Whitley, Chester B,: University of Minnesota. Minneapolis. Minnesota: Retroviral-Mediated Transfer 
of the Iduronate-2-Sulfatase Gene into Lymphocytes for Treatment of Mild Hunter Syndrome 
(Mucopolysaccharidosis Type II). 
RAC Approval: 9-13-94/NIH Approval: Pending 
(T/O/ Peripheral Artery Disease) 
Isner, Jeffrey M. and Walsh, Kenneth; St. Elizabeth’s Medical Center, Tufts University, Boston, 
Massachusetts; Arterial Gene Transfer for Therapeutic Angiogenesis in Patients with Peripheral Artery 
Disease. 
RAC Approval: 9-13-94/NIH Approval: 11-15-94 
(T/C/Malignant Glioma) 
Eck, Stephen L. and Alavi, Jane B,; University of Pennsylvania Medical Center. Philadelphia. 
Pennsylvania: Treatment of Advanced CNS Malignancy with the Recombinant Adenovirus 
H5.020RSVTK: A Phase I Trial. 
RAC Approval: 9-13-94/NTH Approval: Pending 
(T/C/Malignant Mesothelioma) 
Albelda, Steven M,: University of Pennsylvania Medical Center. Philadelphia. Pennsylvania; 
Treatment of Advanced Mesothelioma with the Recombinant Adenovirus H5.010RSVTK : A Phase I 
Trial. 
RAC Approval: 9-13-94/NTH Approval: Pending 
(T/IGD/Cystlc Fibrosis) 
Dorkin, Henry L., New England Medical Center, Tufts University, Boston, Massachusetts; and 
Lapcy, Allen, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; 
Adenovirus Mediated Gene Transfer for Cystic Fibrosis: Safety of Single Administration in the Lung 
( lobar instillation ) . 
NIH/ORDA Approval: 10-5-94 (Accelerated Review) 
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Recombinant DNA Research, Volume 20 
