CLINICAL PROTOCOL 
Product VCL-1102 
August 10 , 1994 
VICAL INC. 
9373 Towne Centre Dr., Ste. 100 
San Diego, CA 92121 
43. O'Quigley J, Chevret S. Methods for dose finding studies in cancer clinical trials: 
A review and results of a monte carlo study. Statistics in Medicine 10:1647-1664, 
1991. 
44. O'Quigley J, Pepe M, Fisher L. Continual reassessment method: A practical 
design for phase I clinical trials in cancer. Biometrics 46:33-48, 1990. 
14.0 APPENDICES 
Appendices 1-3 are attached. 
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