Protocol 
Gene Therapy of Primary and Metastatic Malignant Tumors of the Liver Using 
ACN53 Via Hepatic Artery Infusion: A Phase I Study 
Product: 
Recombinant adenovirus containing the cloned 
human wild-type p53 tumor suppressor gene 
(ACN53) 
UCSF Protocol Number: 
45294 
Principal Investigator: 
Alan P. Venook, M.D. 
Robert S. Warren, M.D 
Associate Investigators: 
Thierry Jahan, M.D. 
Ernest Ring, M.D. 
Medfcar Monitor: 
JohrrWrPark, M.D. 
Company Sponsor: 
Canji, Inc. 
3030 Science Park Road, Suite 302 
San Diego, CA 92121 
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Recombinant DNA Research, Volume 20 
