Fig. 5 Photomicrographs of coronal sections of brains from treated and untreated mice. A, 
a TK+G- treated animal showing the presence of a large tumor (outlined by arrows). B, 
higher magnification of the tumor in figure A showing the carbon particles used to mark the 
adenovirus injection site. C, a TK+G+ treated animal showing a small residual tumor along 
the needle tract (arrow). D, detail of the residual tumor at the site indicated by the arrow in 
figure C showing carbon particles. E, a TK+G+ treated animal with no residual tumor. F, 
detail of injection site in figure D showing red blood cells, macrophages, and carbon 
particles at the site marked by the arrow in panel E. Bars equal 1 mm (A.C.E) and 50 mm 
(B,D,F). 
Recombinant DNA Research, Volume 20 
