( »* ) 
V* An Abflratt out of a Letter from DoFlor 
W. Holbrooke of Manchefter, to Dr. W. Cole, 
Fellow of the College of Fhyjitians in London 3 
concerning Stones "Voided by Stoole . With Dr. Cole’j 
Anfwer to the fame. 
Manchejler , September 4, 1700. 
S I R, 
I Muft beg your Patience a while longer, and defire 
your Thoughts of what I think a remarkable Cafe, 
One Crumbleholm came to me fometime ago, and com- 
plain’d of a great lofs of Appetite, with Scorbutick Itch, 
and ever and anon fevere Convulfive Cholicks below 
his Navel, all along the Hypogaflrium. They la ft not 
above a quarter of an Hour, but often return, and raife 
Tumours the bignefs of a large Walnut, which difap* 
pear and remove as the Pain fhifts. He has been trou- 
bled with it fome Years, and took Phyfick of almoft 
every one he met with 5 but, as far as I can perceive, 
not in any regular Method, which gave me fome hopes, 
that T might relieve him. Accordingly I began with 
mild Emollient and Carminative Glyfters 5 purged with 
Decott. Sen. Gereon. Syr. de Spin, cervin. & Tint}. Sdcr. 
In the Intervals of the Purges I gave JEthiops Mineral, 
with bitterDeeo&ions Alterative, made more Carminative 
with Rtf Zedoar. and Cajior. He was relieved for that 
pnrpofe 5 his Appetite and Complexion mended, but 
prefentiy was as 111 as ever. Then he (how’d me the 
Stones voided by Stoole, upon a flight Mercurial Purge, 
which he took laft Eajler. Upon opening one of them, 
I 
