830 SUMMARY OF CURRENT RESEARCHES RELATING TO 
a Blastomycete which is cultivable in bouillon containing glucose and 
tartaric acid, and also on solid media with an acid reaction. The acidity 
of the culture medium is an interesting feature, inasmuch as the reaction 
of central nervous tissue is acid. Injection of pure cultures into animals 
(guinea-pigs, dogs, rabbits) proved fatal after a lengthy incubation 
period. The symptoms of the disease resembled those of rabies, the most 
prominent phenomenon being paralysis. 
Cattle Malaria.* — Herren A. Celli and F. S. Santorini describe a 
disease affecting cattle in the Roman Campagna, which is characterised 
by fever, anaemia, occasionally by haemoglobinuria, and always by 
the presence of endoglobular parasites in the blood. This disease is 
apparently identical with Texas fever (Smith, Kilborne), haemoglobi- 
nuria (Babes), and hematinuria (Sanfelice). The parasite appears 
under two forms, one exhibiting merely local movements within the red 
corpuscles, the other manifesting amoeboid movements. The former 
is from 1—1*5 /x in size, and the latter two or three times as large. The 
amoeboid form often exactly resembles the Pyrosoma bigeminum (Smith). 
The exact relationship between the two forms and the reproduction 
stages were not clearly made out. 
Classification of Malaria Parasites.f — Dr. X. Lewkowicz divides 
the htemosporidia of malaria into two groups. In Group I. the develop- 
mental stage of the sporidia lasts for 2 to 3 days ; development is endo- 
globular, and the adult form spheroidal. The species of this group are 
H. tertianee , having a developmental period of 2 days, and H. quartcinse, 
with one of 3 days. 
In Group II. the developmental period is more than 3 days, and 
development is extraglobular, the adult being crescent-shaped. Four 
species of this group are enumerated : — H. undecimanse , with a develop- 
mental period of 10 days ; H. sedecimanse , of 15 days ; H. vegesimo- 
tertianse, of 22 days ; and H. (?), with an undetermined period of sporidia 
develo|)inent, the adult form of this variety being cigar-shaped. 
Microbes of Yellow Fever. — Prof. G. Sanarelli + has isolated 
from the blood of persons affected with yellow fever a bacillus varying 
in size from 2-4 /x, and as a rule twice or thrice longer than broad. Its 
ends are rounded, it is very pleomorphous, and is mostly found in little 
groups in the capillaries of the kidney, liver, &c. The best way to 
demonstrate it is to begin by incubating a piece of fresh liver at 37° C. 
for 12 hours. The bacillus grows well on gelatin, which is not lique- 
fied. Agar cultures afford an important means of diagnosis; for when 
incubated at 37°, the colonies are roundish, grey, smooth, and transparent ; 
but if grown at 20°-22°, the colonies are like drops of milk, opaque, 
prominent, and with pearly reflections. The bacillus is a facultative 
anaerobe, stains well, ferments sugar, but does not coagulate milk ; it 
strongly resists drying, dies in water at 60°, but lives for a long time in 
sea water, and is killed in 7 hours by sun-rays. It is pathogenic to 
most domestic animals, except birds, the chief lesions found after death 
being fatty degeneration of the liver, hematogenous gastro-enteritis, 
* Centralbl. Baht. u. Par , l ta Abt., xxi. (1897) pp. 561-72 (1 pi. and 56 figs.).. 
t Tom. cit., pp. 129-33. 
X Brit. Med. Journ., 1897, ii. pp. 7-11 ; and Ann. Inst. Pasteur, xi. (1897) 
pp. 433-514 (9 pis.). 
