772 
SUM2IARY OF CURRENT RESEARCHES RELATING TO 
Details are then given as to the treatment of lupus, tuberculosis of 
bones and joints, and of phthisis, from which we will only quote two 
paragraphs. 
“ The action of the remedy in cases of phthisis generally showed 
itself as follows : — Cough and expectoration generally increased a little 
after the first injection, then grew less and less, and in the most favour- 
able cases entirely disappeared ; the expectoration also lost its purulent 
character and became mucous. 
As a rule, the number of bacilli only decreased when the expectora- 
tion began to present a mucous appearance ; they then from time to 
time disappeared entirely, but were again observed occasionally until 
expectoration ceased completely. Simultaneously the night sweats 
ceased, the patients’ appearance improved, and they increased in weight. 
Within four to six weeks patients under treatment for the first stage of 
phthisis were all free from every symptom of disease, and might be 
pronounced cured. Patients wdth cavities not yet too highly developed 
improved considerably, and were almost cured ; only in those whose 
lungs contained many large cavities could no improvement be proved 
objectively, though even in these cases the expectoration decreased, and 
the subjective condition improved. These experiences lead me to suppose 
that 'phthisis in the beginning can be cured with certainty by this remedy”* 
Baumgarten and others. — Jahresbericht iib. die Fortscbritte in der Lebre v. 
den patbogenen Mikro-organismen, umfassend Bakterien, Pilze u. Protozoen. 
Unter Mitwirkung mehrer Fachgenossen bearb. u. hrsg. v. P. Baumgarten. 
(Annual Report on the progress of our knowledge of Pathogenic Micro-organisms, 
inclusive of Bacteria, Fungi, and Protozoa. 4tb year.) 
4ter Jabrg. 1888, 2te Half te, Braunschweig, large 8vo, pp.ix.-xi. and 257-587. 
Bouchard, Ch. — Action des prodnits secretes par les microbes pathogenes. 
(Action of the products secreted by pathogenic microbes.) Paris, 1890, 4to. 
Charrin, A. — Sur certaines actions physiologiques des secretions microbiennes. 
(On certain physiological actions of the secretions of microbes.) 
Arch, de Physiol ., 1890, pp. 625-7. 
Cornil, A. v., et Y. Babes. — Les bacteries. (The Bacteria.) 
Paris, 1890, 2 vols. 8vo, 385 figs, and 12 pis. 
Danilewski, V. — Developpement des parasites malariques dans le sang des 
oiseaux. (Development of malarial parasites in the blood of birds.) 
Annal. de VInstitut Pasteur , 1890, p. 427. 
„ „ Contribution a l’etude des phagocytes. (Contribution to the 
study of phagocytes.) T. c , pp. 432-9. 
G abritchewsky. — Contribution a l’etude de la parasitologie du sang. (Con- 
tribution to the study of parasites in the blood.) T. c., p. 442. 
Hafkine, W. M. — Recherches sur l’adaptation au milieu chez les infusoires et 
les bacteries ; contribution a l’etude de l’immunite. (Researches on adaptation 
to environment in Infusoria and Bacteria ; a contribution to the study of 
immunity.) T. c., pp. 363-79. 
Holst, A. — Oversigt over bakteriologien for lseger og studerende. (Handbook 
of Bacteriology.) 8vo, Christiania, 1890. 
* « This sentence requires limitation in so far as at present no conclusive ex- 
periences can possibly be brought forward to prove whether the cure is lasting. 
Relapses naturally may occur ; but it can be assumed that they may be cured as 
easily and quickly as the first attack. On the other hand, it seems possible that, as 
in other infectious diseases, patients once cured may retain their immunity. This, 
too, must for the present remain an open question.” 
