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SUMMARY OF CURRENT RESEARCHES RELATING TO 
together with the formation of a considerable swelling at the site of 
the mallein injection, and general symptoms of disease, are indicative of 
glanders. Their observations show that in both glandered and healthy 
horses there is an initial fall of a tenth of a degree after the mallein 
injection. After some hours the temperature begins to rise, attaining 
its maximum in 8 to 15 hours after the injection. In glandered horses 
the temperature rises usually 2°-3°, sometimes 3° • 5, in healthy ones 
0° • 7 to 0° * 8 , rarely to 1°. In horses suffering from other diseases the 
temperature may ascend l°-2°, but there is no tumour formation. The 
tumour usually begins to form some honrs after injection, and in 
glandered horses increases till the second or third day. In healthy 
horses, should it occur, it disappears on the injection day. 
Tuberculosis in a Lioness.* — M. J. Straus had the opportunity of 
examining a five-year-old lioness who in the last months of her captivity 
(4 years) had become emaciated almost to a skeleton. The post-mortem 
revealed “ fibroid phthisis ” of both lungs, with numerous small cavities 
in the contents of which the tubercle bacillus was found. The sections 
showed caseating tubercles with bacilli. Tubercles were not found 
in the other organs. This case seems to show that the infection had 
taken place through inhalation, and not from feeding, as is usually the 
case with animals kept in captivity. 
Sensitiveness of Marmot to Vibrio Metchnikovi. f — Herr W. 
Palmirsky finds that the earless Marmot ( Sjpermopliilus citillus ), a great 
plague in South Kussia, is extremely sensitive to Vibrio Metchnikovi . 
By feeding the animals on corn infected with this bacillus they speedily 
die, and the dead animals communicate the disease to their companions. 
The author suggests that Vibrio Metchnikovi might bemused for deci- 
mating or even extirpating these destructive rodents. 
Antirabic Vaccination with Virus attenuated by Heat.J — MM. E. 
Puscarin and M. Vesesco record some experiments made for the purpose 
of determining whether an efficacious hydrophobia vaccine can be 
obtained by means of heat, their object being not so much scientific as 
the saving of expense and the prevention of some inconvenience. They 
conclude that it is possible to obtain a vaccine by such a method, but at 
present their system is not properly organised by sufficient observations. 
Increasing the Virulence of Diphtheria Bacilli and the Antitoxic 
Serum.§— By passing diphtheria bacilli, which have lost much of their 
original virulence through age, through a series of animals, Dr. J. 
Bardach finds that this virulence may be restored. Thus, after 25 pass- 
ages through dogs were obtained cultures of which 0 • 25 ccm. was fatal to 
dogs and 0*015 ccm. to guinea-pigs. The virulence had been increased 
80-fold and these passages through dogs had increased the virulence 
more for dogs than for guinea-pigs. The diphtheria bacilli, therefore, 
had adapted themselves for the struggle against the cells of the canine 
organism. The vaccination of dogs by continually increasing doses of 
cultures is then described. After every injection there was marked local 
* Arch. Med. Exp. et d’Anat. Pathol., vi. (1894) p. 645. See Centralbl. & 
Bakteriol. u. Parasitenk. (P Abt.), xvii. (1895) p. 96. 
t Arch. Sci. Biol. Inst. Imp. Med. Exp. St. Petersbourg, ii. (1893) pp. 497-503. 
X Ann. Inst. Pasteur, ix. (1895) pp. 210-3. t § Tom. cit., pp. 40-55.] 
