ZOOLOGY AND BOTANY, MICROSCOPY, ETC. 
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life-history of tho Protozoa of cancer, from the time when the parasite 
appears as a spore in the nucleus to tho time when it leaves the latter 
as a young fully-formed parasite, and ho expresses the hope that tho 
later stages in the life-history will soon bo solved. 
Coccidia of Mice.* — Dr. Schuberg has succeeded in breeding spores 
and sickle-germs by cultivating in water Coccidia cysts obtained from 
the intestine of mice. The Coccidia cysts are characterized by a rela- 
tively thick wall and by contents heaped up together like a ball, 
which differ from those of G. oviforme only in being somewhat smaller 
and rounder. Occasionally these cysts were found inside an epithelial 
cell, but more frequently formed small masses on the surface of the 
mucosa. No further stage of development was observed in the intestine, 
and it was only by keeping their faeces moist or under water that suc- 
cessful results were obtained. After two or three days under water 
the contents of the cysts were found to have undergone tetrapartite 
fission. Each of these four portions became eventually surrounded by 
a definite membrane, and developed within it two sickle-shaped germs 
and a residual body. The former are pointed at both ends, and homo- 
geneous in appearance ; the latter oval and granular. 
The opinion is expressed that Eimeria falciformis is probably a 
stage in the development of this Coccidium, and if so it might be named 
C. falciforme. 
* SB. Physik.-Med. Gesell. zu Wurzburg, 1892, pp. 65-72. 
1893 , 
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