ZOOLOGY AND BOTANY, MICROSCOPY, ETC. G99 
enlarge and tlie protoplasm gradually vanishes, after which the former 
divides up into so many small balls which represent spores. The cells 
inhabited by these corpuscles undergo a slow change which ends in 
necrosis. The spore enters (in some way) a young epithelial cell and 
there completes its development, i. e. until it becomes a cystic body 
containing spores. 
Mr. J. J. Clarke * * * § in some observations on the histology of cancer, 
remarks of the Sporozoa which he had previously described, that these 
parasites are in some of their phases identical with those described by 
L. Pfeiffer, L. Wickham, Korotneff and Kurloff. Of epithelial pearls these 
bodies constitute the greater part. They are distinguished by their dense 
texture, their high refracting power, by their size and staining reactions. 
Their shape is most varied. That they are not devoid of vital activity 
is shown by the presence of mitotic figures with achromatic filaments. 
The author’s illustrations, which are double stained (Ehrlich-Biondi), 
represent bodies, some with faintly laminated capsules and corpuscular 
contents stained red and green, some with thin doubly contoured capsules 
also containing corpuscular elements. 
Dr. A. Ruffer,j who has always found that the cancer-body is 
invariably present in carcinoma, agrees with Foa as to its appearances, 
and with Duplay and Cazin that the Coccidia described by Wickham, 
Korotneff, Sawtschenko and others are cell-degenerations. For some time 
the author has studied, in conjunction with Plimmer, the appearances in 
fresh cancer juice. With oblique illumination the parasite can be seen 
quite well, and not unfrequently can be distinguished from the nucleus. 
Sometimes they thought they could detect movements. By treating the 
preparation with Loeffler’s blue to which some drops of methylen-green 
have been added, a very characteristic reaction is obtained. The cancer- 
cell stains dark blue, the nucleus of the parasite is rose-coloured, and 
its plasma light blue. 
Dr. Pibbert + criticizes the appearances described by the various 
observers who have written on the bodies, the Coccidia and the parasites 
of carcinoma and malignant neoplasms in general, and comes to the con- 
clusion that none of the forms described as cancer parasites have any- 
thing typical about them, and that they can be satisfactorily explained 
as degenerations of the tissue-cell or its nucleus. He does not, however, 
go so far as to say that in the etiology of cancer parasites have no part. 
Tetramitus Nitschei, a Parasite of Goldfish.§ — HerrP. Nitscheand 
Dr. W. Weltner describe a new flagellate parasite on goldfish. It re- 
sembles in some respects Bodo necator Henneguy, an ecto-parasite of 
young trout, but is distinguished therefrom by its smaller size, by the 
possession of four flagella, by the absence of the longitudinal furrow 
which almost divides B. necator into two unequal halves, and by remain- 
ing on the adult fish. Wlien adherent to the fish, T. Nitschei is pear- 
shaped, but when free swimming as observed in a drop of water under 
the Microscope it is oval. At the anterior end is a deepish depression. 
* Centralbl. f. Bakteriol. u. Parasitenk., xvi. (1894) pp. 281-5 (1 pi.). 
f Mitteil. XI. Internat. Med. Kongr. in Rom. See Centralbl. f. Bakteriol. u. 
Parasitenk., xvi. (1894) pp. 460-1. 
+ Deutsche Med. Woclienschr., 1894, No. 15. See Centralbl. f. Bakteriol. u. 
Parasitenk., xv. (1894) pp. 962-5. 
§ Centralbl. f. Bakteriol. u. Parasitenk., xvi. (1894) pp. 25-30 (4 figs.). 
