[J»<] 
i. As to the original or prime Caufe of all the Sym- 
ptoms, to wit, the Diftention of the Gall-Bladder, now 
become a morbid Cyftis of an enormous Extent. 
If we conilder the Size and Figure of the Liver, and 
Situation of the Gall-Bladder, with the Courfe orDi- 
redion of the Biliary Vcffels, from various Places of 
the Liver, towards that narrow Space where the Pori 
biliariio^zw into the Cyftis , it will appear, that in al- 
moft every Pofition of the Body, at lead; in an erect, 
fupine and lateral Pofition, forneof thefc biliary Duds 
terminating in the Gall-Bladder, are perpendicular or 
nearly perpendicular to the Horizon and to the Cyftis : 
Therefore, as far as Gravity takes Place in the Animal 
Oeconomy, the Bile defeending by thefe Duds, will 
prefs upon the Contents of the full Cyftis and its Sides, 
as a Cylinder of that Fluid, of the Length of the Se- 
cretory Duds or Pipes, and of the Diameter of the 
Cyftis. 
Befides this, the Extremity of every one of thefe 
fmall Duds, conveys its Fluid into the full Cyftis , as 
a Wedge aded upon by the repeated Strokes, Impulfes, 
or Prefiure of the circulating Blood of the Vena Porta , 
where it fupplies the Gland at the Origine of each Pe- 
er etory Dud. 
Therefore, by the known Laws of Hydrofta- 
ticks and Mechanicks, it is apparent, that the Force 
of this Secretion of the Bile into the Gall-Bladder is 
very great, and the Quantity copious 5 fufficient at lead 
to diftend the Cyftis to an enormous Pitch, where the 
Difcharge by the 'DuEtus cyfticus is not equal to the 
Secretion by the Pori biliairi and the EDuEfus hepatico- 
cyfticus , 
- Thefe 
