448 
H. M. WOODCOCK AND 0. LAPAGE. 
fine granules closely arranged round the periphery (figs. 30- 
41), or, more rarely, comprising fewer, somewhat more pro- 
minent granules (figs. 45, 46, 49). We have not found any 
ovals with one or two large, deeply staining masses of 
chromatin such as are shown by some of the crescents. 
Farther, the ovals divide in just the same way, by equal, trans- 
verse, binary fission (figs. 49-53). Whatever the crescents 
are, we think there can be no doubt that these ovals are, ;it 
any rate, a very similar type of thing (c f . especially figs. 6, 
27 of crescents with figs. 40, 53 of ovals) ; the only essential 
point of difference is that the latter have no flagellum. 
In the great majority of the ovals which show the second 
type of minute structure, the envelope projects markedly at 
both ends of the body (figs. 65-69), and now and again it 
stands off slightly also at the sides (figs. 64, 66, and fig. 87 
on a Giemsa smear). The general protoplasm is usually 
sharply divided into two distinct zones, a central, lighter- 
staining region and a peripheral, more deeply staining area, 
which is usually^ wider at the two ends. The lighter staining, 
central area appears very similar to the general cytoplasm of 
the other ovals, and is, we consider, comparable to that. The 
darker-staining zone appears practically homogeneous, and 
does not contain, or is not composed of, the fine intensely 
stainins: sfranules characterising the chromatinic zone of the 
first type of ovals. The comparative extent of the central 
pale area and the surrounding darker region varies greatly in 
different individuals. In some the central area is small and 
the dark zone thick and broad (figs. 65, 67, 68) ; in others the 
paler area is much increased and the peripheral zone reduced 
to a narrow band (figs. 58, 59). Frequently, with this 
increase of the paler area, the dark-staining substance 
persists chiefly in the form of two caps, one at each end of 
the oval, connected only along the two sides of the oval by 
an extremely thin peripheral layer (figs. 60, 69). Lastly, in 
a small proportion of ovals, all the protoplasm appears to 
consist of the darker-staining substance (figs. 64, 70) ; these 
may be either small or fairly large. 
